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Oxidation of aminoalkyl and hydroxylaminoalkyl furans

Kazancioglu, Mustafa Zahrittin; Kazancioglu, Elif Akin; Secen, Hasan; Altundas, Ramazan


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{
  "@context": "https://schema.org/", 
  "@id": 82287, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Ataturk Univ, Dept Chem, Coll Sci, TR-25240 Erzurum, Turkey", 
      "name": "Kazancioglu, Mustafa Zahrittin"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ataturk Univ, Dept Chem, Coll Sci, TR-25240 Erzurum, Turkey", 
      "name": "Kazancioglu, Elif Akin"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ataturk Univ, Dept Chem, Coll Sci, TR-25240 Erzurum, Turkey", 
      "name": "Secen, Hasan"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ataturk Univ, Dept Chem, Coll Sci, TR-25240 Erzurum, Turkey", 
      "name": "Altundas, Ramazan"
    }
  ], 
  "datePublished": "2015-01-01", 
  "description": "The oxidation reactions of amino and hydroxylamino substituted alkylfurans were explored for the synthesis of structurally complex compounds from simple starting materials. A novel photooxygenation of the furan derivatives gave an alpha,beta-unsaturated dicarbonyl moiety which underwent subsequent conjugate addition to yield diastereomeric mixtures of the corresponding pyrrolidine and isoxazoline heterocycles. Oxidation of the alpha,beta-unsaturated dicarbonyl using mCPBA gave epoxide intermediates, which were opened by nucleophilic attack of the amino groups, furnishing pyrrolidine and isoxazolidine heterocycles. (C) 2015 Elsevier Ltd. All rights reserved.", 
  "headline": "Oxidation of aminoalkyl and hydroxylaminoalkyl furans", 
  "identifier": 82287, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Oxidation of aminoalkyl and hydroxylaminoalkyl furans", 
  "url": "https://aperta.ulakbim.gov.tr/record/82287"
}
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