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Concise design and synthesis of pyridine-fused heterocycles via 6 pi- Azaelectrocyclization process of iminoalkyne derivatives

Sendil, Kivilcim; Keskin, Selbi; Balci, Metin


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{
  "DOI": "10.1016/j.tet.2019.130660", 
  "abstract": "A concise and regioselective approach to the synthesis of pyridine-fused heterocycles and benzoxazepine derivatives was developed. Propargyl imines derived from aromatic aldehydes and propargyl amine underwent 6 pi-electrocyclization reactions at high temperatures in high yields to form pyridine-fused heterocycles. Application of the same methodology to aromatic imines having a hydroxyl group in the ortho position resulted in the formation of (benz)oxazepine derivatives. The formation mechanism of the products was discussed. (C) 2019 Elsevier Ltd. All rights reserved.", 
  "author": [
    {
      "family": "Sendil", 
      "given": " Kivilcim"
    }, 
    {
      "family": "Keskin", 
      "given": " Selbi"
    }, 
    {
      "family": "Balci", 
      "given": " Metin"
    }
  ], 
  "container_title": "TETRAHEDRON", 
  "id": "74961", 
  "issue": "46", 
  "issued": {
    "date-parts": [
      [
        2019, 
        1, 
        1
      ]
    ]
  }, 
  "title": "Concise design and synthesis of pyridine-fused heterocycles via 6 pi- Azaelectrocyclization process of iminoalkyne derivatives", 
  "type": "article-journal", 
  "volume": "75"
}
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