1 Ocak 2019 Dergi makalesi Açık Erişim

Bugan, Ilknur; Kucuk, Selma; Karagoz, Zeynep; Fraser, Scott P.; Kaya, Handan; Dodson, Andrew; Foster, Christopher S.; Altun, Seyhan; Djamgoz, Mustafa B. A.

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  "@id": 71757, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Istanbul Univ, Fac Sci, Dept Biol, TR-34134 Istanbul, Turkey", 
      "name": "Bugan, Ilknur"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Istanbul Univ, Fac Sci, Dept Biol, TR-34134 Istanbul, Turkey", 
      "name": "Kucuk, Selma"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Istanbul Univ, Fac Sci, Dept Biol, TR-34134 Istanbul, Turkey", 
      "name": "Karagoz, Zeynep"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Imperial Coll London, Dept Life Sci, Sir Alexander Fleming Bldg, London SW7 2AZ, England", 
      "name": "Fraser, Scott P."
    }, 
    {
      "@type": "Person", 
      "affiliation": "Marmara Univ, Dept Pathol, Sch Med, Istanbul, Turkey", 
      "name": "Kaya, Handan"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Inst Canc Res, Fulham Rd, London SW3 6JB, England", 
      "name": "Dodson, Andrew"
    }, 
    {
      "@type": "Person", 
      "affiliation": "HCA Healthcare UK, Cellular Pathol Labs, GPS House,215 Great Portland St, London W1W 5PN, England", 
      "name": "Foster, Christopher S."
    }, 
    {
      "@type": "Person", 
      "affiliation": "Istanbul Univ, Fac Sci, Dept Biol, TR-34134 Istanbul, Turkey", 
      "name": "Altun, Seyhan"
    }, 
    {
      "@type": "Person", 
      "name": "Djamgoz, Mustafa B. A."
    }
  ], 
  "datePublished": "2019-01-01", 
  "description": "Background Voltage-gated Na+ channels (VGSCs) are functionally upregulated in rat and human prostate cancer (PCa) where channel activity promotes cellular invasiveness in vitro and metastasis in vivo. Ranolazine is a clinically used VGSC inhibitor/anti-anginal drug, which has been shown previously to inhibit breast cancer metastasis in vivo.", 
  "headline": "Anti-metastatic effect of ranolazine in an in vivo rat model of prostate cancer, and expression of voltage-gated sodium channel protein in human prostate", 
  "identifier": 71757, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Anti-metastatic effect of ranolazine in an in vivo rat model of prostate cancer, and expression of voltage-gated sodium channel protein in human prostate", 
  "url": "https://aperta.ulakbim.gov.tr/record/71757"
}