Dergi makalesi Açık Erişim

Anti-metastatic effect of ranolazine in an in vivo rat model of prostate cancer, and expression of voltage-gated sodium channel protein in human prostate

Bugan, Ilknur; Kucuk, Selma; Karagoz, Zeynep; Fraser, Scott P.; Kaya, Handan; Dodson, Andrew; Foster, Christopher S.; Altun, Seyhan; Djamgoz, Mustafa B. A.


JSON

{
  "conceptrecid": "71756", 
  "created": "2021-03-16T03:33:45.669420+00:00", 
  "doi": "10.1038/s41391-019-0128-3", 
  "files": [
    {
      "bucket": "1b966766-816b-41e4-893e-f711dc46ba48", 
      "checksum": "md5:4761cf33574c3e030b80bd61dbc9a9a0", 
      "key": "bib-22e6981d-7514-488a-a042-cac51b39bfe9.txt", 
      "links": {
        "self": "https://aperta.ulakbim.gov.tr/api/files/1b966766-816b-41e4-893e-f711dc46ba48/bib-22e6981d-7514-488a-a042-cac51b39bfe9.txt"
      }, 
      "size": 323, 
      "type": "txt"
    }
  ], 
  "id": 71757, 
  "links": {
    "badge": "https://aperta.ulakbim.gov.tr/badge/doi/10.1038/s41391-019-0128-3.svg", 
    "bucket": "https://aperta.ulakbim.gov.tr/api/files/1b966766-816b-41e4-893e-f711dc46ba48", 
    "doi": "https://doi.org/10.1038/s41391-019-0128-3", 
    "html": "https://aperta.ulakbim.gov.tr/record/71757", 
    "latest": "https://aperta.ulakbim.gov.tr/api/records/71757", 
    "latest_html": "https://aperta.ulakbim.gov.tr/record/71757"
  }, 
  "metadata": {
    "access_right": "open", 
    "access_right_category": "success", 
    "communities": [
      {
        "id": "tubitak-destekli-proje-yayinlari"
      }
    ], 
    "creators": [
      {
        "affiliation": "Istanbul Univ, Fac Sci, Dept Biol, TR-34134 Istanbul, Turkey", 
        "name": "Bugan, Ilknur"
      }, 
      {
        "affiliation": "Istanbul Univ, Fac Sci, Dept Biol, TR-34134 Istanbul, Turkey", 
        "name": "Kucuk, Selma"
      }, 
      {
        "affiliation": "Istanbul Univ, Fac Sci, Dept Biol, TR-34134 Istanbul, Turkey", 
        "name": "Karagoz, Zeynep"
      }, 
      {
        "affiliation": "Imperial Coll London, Dept Life Sci, Sir Alexander Fleming Bldg, London SW7 2AZ, England", 
        "name": "Fraser, Scott P."
      }, 
      {
        "affiliation": "Marmara Univ, Dept Pathol, Sch Med, Istanbul, Turkey", 
        "name": "Kaya, Handan"
      }, 
      {
        "affiliation": "Inst Canc Res, Fulham Rd, London SW3 6JB, England", 
        "name": "Dodson, Andrew"
      }, 
      {
        "affiliation": "HCA Healthcare UK, Cellular Pathol Labs, GPS House,215 Great Portland St, London W1W 5PN, England", 
        "name": "Foster, Christopher S."
      }, 
      {
        "affiliation": "Istanbul Univ, Fac Sci, Dept Biol, TR-34134 Istanbul, Turkey", 
        "name": "Altun, Seyhan"
      }, 
      {
        "name": "Djamgoz, Mustafa B. A."
      }
    ], 
    "description": "Background Voltage-gated Na+ channels (VGSCs) are functionally upregulated in rat and human prostate cancer (PCa) where channel activity promotes cellular invasiveness in vitro and metastasis in vivo. Ranolazine is a clinically used VGSC inhibitor/anti-anginal drug, which has been shown previously to inhibit breast cancer metastasis in vivo.", 
    "doi": "10.1038/s41391-019-0128-3", 
    "has_grant": false, 
    "journal": {
      "issue": "4", 
      "pages": "569-579", 
      "title": "PROSTATE CANCER AND PROSTATIC DISEASES", 
      "volume": "22"
    }, 
    "license": {
      "id": "cc-by"
    }, 
    "publication_date": "2019-01-01", 
    "relations": {
      "version": [
        {
          "count": 1, 
          "index": 0, 
          "is_last": true, 
          "last_child": {
            "pid_type": "recid", 
            "pid_value": "71757"
          }, 
          "parent": {
            "pid_type": "recid", 
            "pid_value": "71756"
          }
        }
      ]
    }, 
    "resource_type": {
      "subtype": "article", 
      "title": "Dergi makalesi", 
      "type": "publication"
    }, 
    "title": "Anti-metastatic effect of ranolazine in an in vivo rat model of prostate cancer, and expression of voltage-gated sodium channel protein in human prostate"
  }, 
  "owners": [
    1
  ], 
  "revision": 1, 
  "stats": {
    "downloads": 8.0, 
    "unique_downloads": 8.0, 
    "unique_views": 39.0, 
    "version_downloads": 8.0, 
    "version_unique_downloads": 8.0, 
    "version_unique_views": 39.0, 
    "version_views": 41.0, 
    "version_volume": 2584.0, 
    "views": 41.0, 
    "volume": 2584.0
  }, 
  "updated": "2021-03-16T03:33:45.721784+00:00"
}
41
8
görüntülenme
indirilme
Görüntülenme 41
İndirme 8
Veri hacmi 2.6 kB
Tekil görüntülenme 39
Tekil indirme 8

Alıntı yap