Dergi makalesi Açık Erişim
Bugan, Ilknur; Kucuk, Selma; Karagoz, Zeynep; Fraser, Scott P.; Kaya, Handan; Dodson, Andrew; Foster, Christopher S.; Altun, Seyhan; Djamgoz, Mustafa B. A.
{ "DOI": "10.1038/s41391-019-0128-3", "abstract": "Background Voltage-gated Na+ channels (VGSCs) are functionally upregulated in rat and human prostate cancer (PCa) where channel activity promotes cellular invasiveness in vitro and metastasis in vivo. Ranolazine is a clinically used VGSC inhibitor/anti-anginal drug, which has been shown previously to inhibit breast cancer metastasis in vivo.", "author": [ { "family": "Bugan", "given": " Ilknur" }, { "family": "Kucuk", "given": " Selma" }, { "family": "Karagoz", "given": " Zeynep" }, { "family": "Fraser", "given": " Scott P." }, { "family": "Kaya", "given": " Handan" }, { "family": "Dodson", "given": " Andrew" }, { "family": "Foster", "given": " Christopher S." }, { "family": "Altun", "given": " Seyhan" }, { "family": "Djamgoz", "given": " Mustafa B. A." } ], "container_title": "PROSTATE CANCER AND PROSTATIC DISEASES", "id": "71757", "issue": "4", "issued": { "date-parts": [ [ 2019, 1, 1 ] ] }, "page": "569-579", "title": "Anti-metastatic effect of ranolazine in an in vivo rat model of prostate cancer, and expression of voltage-gated sodium channel protein in human prostate", "type": "article-journal", "volume": "22" }
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