Dergi makalesi Açık Erişim

Anti-metastatic effect of ranolazine in an in vivo rat model of prostate cancer, and expression of voltage-gated sodium channel protein in human prostate

Bugan, Ilknur; Kucuk, Selma; Karagoz, Zeynep; Fraser, Scott P.; Kaya, Handan; Dodson, Andrew; Foster, Christopher S.; Altun, Seyhan; Djamgoz, Mustafa B. A.


Citation Style Language JSON

{
  "DOI": "10.1038/s41391-019-0128-3", 
  "abstract": "Background Voltage-gated Na+ channels (VGSCs) are functionally upregulated in rat and human prostate cancer (PCa) where channel activity promotes cellular invasiveness in vitro and metastasis in vivo. Ranolazine is a clinically used VGSC inhibitor/anti-anginal drug, which has been shown previously to inhibit breast cancer metastasis in vivo.", 
  "author": [
    {
      "family": "Bugan", 
      "given": " Ilknur"
    }, 
    {
      "family": "Kucuk", 
      "given": " Selma"
    }, 
    {
      "family": "Karagoz", 
      "given": " Zeynep"
    }, 
    {
      "family": "Fraser", 
      "given": " Scott P."
    }, 
    {
      "family": "Kaya", 
      "given": " Handan"
    }, 
    {
      "family": "Dodson", 
      "given": " Andrew"
    }, 
    {
      "family": "Foster", 
      "given": " Christopher S."
    }, 
    {
      "family": "Altun", 
      "given": " Seyhan"
    }, 
    {
      "family": "Djamgoz", 
      "given": " Mustafa B. A."
    }
  ], 
  "container_title": "PROSTATE CANCER AND PROSTATIC DISEASES", 
  "id": "71757", 
  "issue": "4", 
  "issued": {
    "date-parts": [
      [
        2019, 
        1, 
        1
      ]
    ]
  }, 
  "page": "569-579", 
  "title": "Anti-metastatic effect of ranolazine in an in vivo rat model of prostate cancer, and expression of voltage-gated sodium channel protein in human prostate", 
  "type": "article-journal", 
  "volume": "22"
}
41
8
görüntülenme
indirilme
Görüntülenme 41
İndirme 8
Veri hacmi 2.6 kB
Tekil görüntülenme 39
Tekil indirme 8

Alıntı yap