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Serum choline and butyrylcholinesterase changes in response to endotoxin in calves receiving intravenous choline administration

Inan, O. Eralp; Tvarijonaviciute, A.; Kocaturk, M.; Rubio, C. P.; Kasap, S.; Cansev, M.; Ceron, J. J.; Yilmaz, Z.; Ulus, I. H.


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    "creators": [
      {
        "affiliation": "Eskisehir Osmangazi Univ, Med & Surg Lab Anim Res & Practice Ctr, TR-26480 Eskisehir, Turkey", 
        "name": "Inan, O. Eralp"
      }, 
      {
        "affiliation": "Univ Murcia, Interlab UMU, Interdisciplinary Lab Clin Pathol, E-30100 Murcia, Spain", 
        "name": "Tvarijonaviciute, A."
      }, 
      {
        "affiliation": "Uludag Univ, Fac Vet Med, Dept Internal Med, TR-16059 Bursa, Turkey", 
        "name": "Kocaturk, M."
      }, 
      {
        "affiliation": "Univ Murcia, Interlab UMU, Interdisciplinary Lab Clin Pathol, E-30100 Murcia, Spain", 
        "name": "Rubio, C. P."
      }, 
      {
        "affiliation": "Uludag Univ, Fac Vet Med, Dept Internal Med, TR-16059 Bursa, Turkey", 
        "name": "Kasap, S."
      }, 
      {
        "affiliation": "Uludag Univ, Fac Med, Dept Pharmacol, TR-16059 Bursa, Turkey", 
        "name": "Cansev, M."
      }, 
      {
        "affiliation": "Univ Murcia, Interlab UMU, Interdisciplinary Lab Clin Pathol, E-30100 Murcia, Spain", 
        "name": "Ceron, J. J."
      }, 
      {
        "affiliation": "Uludag Univ, Fac Vet Med, Dept Internal Med, TR-16059 Bursa, Turkey", 
        "name": "Yilmaz, Z."
      }, 
      {
        "affiliation": "Acibadem Mehmet Ali Aydinlar Univ, Fac Med, Dept Pharmacol, Istanbul, Turkey", 
        "name": "Ulus, I. H."
      }
    ], 
    "description": "Endotoxemia treatment options are still of interest due to high mortality and choline treatment is one of them because of its role in the cholinergic anti-inflammatory pathway. This study investigated serum choline and butyrylcholinesterase (BChE) responses, and their correlations with inflammatory, oxidative stress and tissue damage biomarkers, including paraoxanase-1 (PON1), and clinical signs in calves with endotoxemia and the effect of choline treatment in these responses. Healthy calves (n = 20) were divided equally into 4 groups: Control (0.9% NaCl, iv), Choline (C; 1 mg/kg/iv,once), Lipopolysaccharide (LPS; 2 mu g/kg/iv,once) and LPS + C. Clinical and laboratory examinations were performed before and 0.5-48 h (hrs) after treatments.", 
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      "pages": "290-297", 
      "title": "RESEARCH IN VETERINARY SCIENCE", 
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    "title": "Serum choline and butyrylcholinesterase changes in response to endotoxin in calves receiving intravenous choline administration"
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