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Inan, O. Eralp; Tvarijonaviciute, A.; Kocaturk, M.; Rubio, C. P.; Kasap, S.; Cansev, M.; Ceron, J. J.; Yilmaz, Z.; Ulus, I. H.
{ "DOI": "10.1016/j.rvsc.2019.07.002", "abstract": "Endotoxemia treatment options are still of interest due to high mortality and choline treatment is one of them because of its role in the cholinergic anti-inflammatory pathway. This study investigated serum choline and butyrylcholinesterase (BChE) responses, and their correlations with inflammatory, oxidative stress and tissue damage biomarkers, including paraoxanase-1 (PON1), and clinical signs in calves with endotoxemia and the effect of choline treatment in these responses. Healthy calves (n = 20) were divided equally into 4 groups: Control (0.9% NaCl, iv), Choline (C; 1 mg/kg/iv,once), Lipopolysaccharide (LPS; 2 mu g/kg/iv,once) and LPS + C. Clinical and laboratory examinations were performed before and 0.5-48 h (hrs) after treatments.", "author": [ { "family": "Inan", "given": " O. Eralp" }, { "family": "Tvarijonaviciute", "given": " A." }, { "family": "Kocaturk", "given": " M." }, { "family": "Rubio", "given": " C. P." }, { "family": "Kasap", "given": " S." }, { "family": "Cansev", "given": " M." }, { "family": "Ceron", "given": " J. J." }, { "family": "Yilmaz", "given": " Z." }, { "family": "Ulus", "given": " I. H." } ], "container_title": "RESEARCH IN VETERINARY SCIENCE", "id": "70617", "issued": { "date-parts": [ [ 2019, 1, 1 ] ] }, "page": "290-297", "title": "Serum choline and butyrylcholinesterase changes in response to endotoxin in calves receiving intravenous choline administration", "type": "article-journal", "volume": "125" }
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