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Serum choline and butyrylcholinesterase changes in response to endotoxin in calves receiving intravenous choline administration

Inan, O. Eralp; Tvarijonaviciute, A.; Kocaturk, M.; Rubio, C. P.; Kasap, S.; Cansev, M.; Ceron, J. J.; Yilmaz, Z.; Ulus, I. H.


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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/70617</identifier>
  <creators>
    <creator>
      <creatorName>Inan, O. Eralp</creatorName>
      <givenName>O. Eralp</givenName>
      <familyName>Inan</familyName>
      <affiliation>Eskisehir Osmangazi Univ, Med &amp; Surg Lab Anim Res &amp; Practice Ctr, TR-26480 Eskisehir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Tvarijonaviciute, A.</creatorName>
      <givenName>A.</givenName>
      <familyName>Tvarijonaviciute</familyName>
      <affiliation>Univ Murcia, Interlab UMU, Interdisciplinary Lab Clin Pathol, E-30100 Murcia, Spain</affiliation>
    </creator>
    <creator>
      <creatorName>Kocaturk, M.</creatorName>
      <givenName>M.</givenName>
      <familyName>Kocaturk</familyName>
      <affiliation>Uludag Univ, Fac Vet Med, Dept Internal Med, TR-16059 Bursa, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Rubio, C. P.</creatorName>
      <givenName>C. P.</givenName>
      <familyName>Rubio</familyName>
      <affiliation>Univ Murcia, Interlab UMU, Interdisciplinary Lab Clin Pathol, E-30100 Murcia, Spain</affiliation>
    </creator>
    <creator>
      <creatorName>Kasap, S.</creatorName>
      <givenName>S.</givenName>
      <familyName>Kasap</familyName>
      <affiliation>Uludag Univ, Fac Vet Med, Dept Internal Med, TR-16059 Bursa, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Cansev, M.</creatorName>
      <givenName>M.</givenName>
      <familyName>Cansev</familyName>
      <affiliation>Uludag Univ, Fac Med, Dept Pharmacol, TR-16059 Bursa, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Ceron, J. J.</creatorName>
      <givenName>J. J.</givenName>
      <familyName>Ceron</familyName>
      <affiliation>Univ Murcia, Interlab UMU, Interdisciplinary Lab Clin Pathol, E-30100 Murcia, Spain</affiliation>
    </creator>
    <creator>
      <creatorName>Yilmaz, Z.</creatorName>
      <givenName>Z.</givenName>
      <familyName>Yilmaz</familyName>
      <affiliation>Uludag Univ, Fac Vet Med, Dept Internal Med, TR-16059 Bursa, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Ulus, I. H.</creatorName>
      <givenName>I. H.</givenName>
      <familyName>Ulus</familyName>
      <affiliation>Acibadem Mehmet Ali Aydinlar Univ, Fac Med, Dept Pharmacol, Istanbul, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Serum Choline And Butyrylcholinesterase Changes In Response To Endotoxin In Calves Receiving Intravenous Choline Administration</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2019</publicationYear>
  <dates>
    <date dateType="Issued">2019-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/70617</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1016/j.rvsc.2019.07.002</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Endotoxemia treatment options are still of interest due to high mortality and choline treatment is one of them because of its role in the cholinergic anti-inflammatory pathway. This study investigated serum choline and butyrylcholinesterase (BChE) responses, and their correlations with inflammatory, oxidative stress and tissue damage biomarkers, including paraoxanase-1 (PON1), and clinical signs in calves with endotoxemia and the effect of choline treatment in these responses. Healthy calves (n = 20) were divided equally into 4 groups: Control (0.9% NaCl, iv), Choline (C; 1 mg/kg/iv,once), Lipopolysaccharide (LPS; 2 mu g/kg/iv,once) and LPS + C. Clinical and laboratory examinations were performed before and 0.5-48 h (hrs) after treatments.</description>
  </descriptions>
</resource>
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