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Synthesis of amino-cyclobutanes via [2+2] cycloadditions involving keteniminium intermediates

Kolleth, Amandine; Lumbroso, Alexandre; Tanriver, Gamze; Catak, Saron; Sulzer-Mosse, Sarah; De Mesmaeker, Alain


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  <dc:creator>Kolleth, Amandine</dc:creator>
  <dc:creator>Lumbroso, Alexandre</dc:creator>
  <dc:creator>Tanriver, Gamze</dc:creator>
  <dc:creator>Catak, Saron</dc:creator>
  <dc:creator>Sulzer-Mosse, Sarah</dc:creator>
  <dc:creator>De Mesmaeker, Alain</dc:creator>
  <dc:date>2016-01-01</dc:date>
  <dc:description>We describe an efficient method for the synthesis of aminocyclobutanes via a [2 + 2] cycloaddition between a keteniminium salt and an alkene, followed by a reduction step. The use of easily removable N-allyl moieties as protecting groups increases the potential of this method to access, in a few steps, highly functionalized cyclobutaneamine-containing building blocks. Moreover, DFT calculations verify the compatibility of N-allyl and N-propargyl keteniminiums in [2 + 2] cycloaddition reactions. (C) 2016 Elsevier Ltd. All rights reserved.</dc:description>
  <dc:identifier>https://aperta.ulakbim.gov.trrecord/54513</dc:identifier>
  <dc:identifier>oai:zenodo.org:54513</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://www.opendefinition.org/licenses/cc-by</dc:rights>
  <dc:source>TETRAHEDRON LETTERS 57(25) 2697-2702</dc:source>
  <dc:title>Synthesis of amino-cyclobutanes via [2+2] cycloadditions involving keteniminium intermediates</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
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