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Synthesis of amino-cyclobutanes via [2+2] cycloadditions involving keteniminium intermediates

Kolleth, Amandine; Lumbroso, Alexandre; Tanriver, Gamze; Catak, Saron; Sulzer-Mosse, Sarah; De Mesmaeker, Alain


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{
  "DOI": "10.1016/j.tetlet.2016.04.092", 
  "abstract": "We describe an efficient method for the synthesis of aminocyclobutanes via a [2 + 2] cycloaddition between a keteniminium salt and an alkene, followed by a reduction step. The use of easily removable N-allyl moieties as protecting groups increases the potential of this method to access, in a few steps, highly functionalized cyclobutaneamine-containing building blocks. Moreover, DFT calculations verify the compatibility of N-allyl and N-propargyl keteniminiums in [2 + 2] cycloaddition reactions. (C) 2016 Elsevier Ltd. All rights reserved.", 
  "author": [
    {
      "family": "Kolleth", 
      "given": " Amandine"
    }, 
    {
      "family": "Lumbroso", 
      "given": " Alexandre"
    }, 
    {
      "family": "Tanriver", 
      "given": " Gamze"
    }, 
    {
      "family": "Catak", 
      "given": " Saron"
    }, 
    {
      "family": "Sulzer-Mosse", 
      "given": " Sarah"
    }, 
    {
      "family": "De Mesmaeker", 
      "given": " Alain"
    }
  ], 
  "container_title": "TETRAHEDRON LETTERS", 
  "id": "54513", 
  "issue": "25", 
  "issued": {
    "date-parts": [
      [
        2016, 
        1, 
        1
      ]
    ]
  }, 
  "page": "2697-2702", 
  "title": "Synthesis of amino-cyclobutanes via [2+2] cycloadditions involving keteniminium intermediates", 
  "type": "article-journal", 
  "volume": "57"
}
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