1 Ocak 2017 Dergi makalesi Açık Erişim

Aytac, Zeynep; Yildiz, Zehra Irem; Kayaci-Senirmak, Fatma; Tekinay, Turgay; Uyar, Tamer

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        "affiliation": "Bilkent Univ, Inst Mat Sci & Nanotechnol, UNAM Natl Nanotechnol Res Ctr, TR-06800 Ankara, Turkey", 
        "name": "Aytac, Zeynep"
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        "affiliation": "Bilkent Univ, Inst Mat Sci & Nanotechnol, UNAM Natl Nanotechnol Res Ctr, TR-06800 Ankara, Turkey", 
        "name": "Yildiz, Zehra Irem"
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      {
        "affiliation": "Bilkent Univ, Inst Mat Sci & Nanotechnol, UNAM Natl Nanotechnol Res Ctr, TR-06800 Ankara, Turkey", 
        "name": "Kayaci-Senirmak, Fatma"
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      {
        "name": "Tekinay, Turgay"
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      {
        "affiliation": "Bilkent Univ, Inst Mat Sci & Nanotechnol, UNAM Natl Nanotechnol Res Ctr, TR-06800 Ankara, Turkey", 
        "name": "Uyar, Tamer"
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    "description": "The volatility and limited water solubility of linalool is a critical issue to be solved. Here, we demonstrated the electrospinning of polymer-free nanofibrous webs of cyclodextrin/linalool-inclusion complex (CD/linalool-IC-NFs). Three types of modified cyclodextrin (HP beta CD, M beta CD, and HP gamma CD) were used to electrospin CD/linalool-IC-NFs. Free-standing CD/linalool-IC-NFs facilitate maximum loading of linalool up to 12% (w/w). A significant amount of linalool (45-89%) was preserved in CD/linalool-IC-NFs, due to enhancement in the thermal stability of linalool by cyclodextrin inclusion complexation. Remarkably, CD/linalool-IC-NFs have shown fast-dissolving characteristics in which these nanofibrous webs dissolved in water within two seconds. Furthermore, linalool release from CD/linalool-IC-NFs inhibited growth of model Gram-negative (E. coli) and Gram-positive (S. aureus) bacteria to a great extent. Briefly, characteristics of liquid linalool have been preserved in a solid nanofiber form and designed CD/linalool-IC-NFs confer high loading capacity, enhanced shelf life and strong antibacterial activity of linalool. (C) 2017 Elsevier Ltd. All rights reserved.", 
    "doi": "10.1016/j.foodchem.2017.03.113", 
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    "journal": {
      "pages": "192-201", 
      "title": "FOOD CHEMISTRY", 
      "volume": "231"
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    "publication_date": "2017-01-01", 
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    "title": "Electrospinning of cyclodextrin/linalool-inclusion complex nanofibers: Fast-dissolving nanofibrous web with prolonged release and antibacterial activity"
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