1 Ocak 2017 Dergi makalesi Açık Erişim

Aytac, Zeynep; Yildiz, Zehra Irem; Kayaci-Senirmak, Fatma; Tekinay, Turgay; Uyar, Tamer

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/49911</identifier>
  <creators>
    <creator>
      <creatorName>Aytac, Zeynep</creatorName>
      <givenName>Zeynep</givenName>
      <familyName>Aytac</familyName>
      <affiliation>Bilkent Univ, Inst Mat Sci &amp; Nanotechnol, UNAM Natl Nanotechnol Res Ctr, TR-06800 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Yildiz, Zehra Irem</creatorName>
      <givenName>Zehra Irem</givenName>
      <familyName>Yildiz</familyName>
      <affiliation>Bilkent Univ, Inst Mat Sci &amp; Nanotechnol, UNAM Natl Nanotechnol Res Ctr, TR-06800 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Kayaci-Senirmak, Fatma</creatorName>
      <givenName>Fatma</givenName>
      <familyName>Kayaci-Senirmak</familyName>
      <affiliation>Bilkent Univ, Inst Mat Sci &amp; Nanotechnol, UNAM Natl Nanotechnol Res Ctr, TR-06800 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Tekinay, Turgay</creatorName>
      <givenName>Turgay</givenName>
      <familyName>Tekinay</familyName>
    </creator>
    <creator>
      <creatorName>Uyar, Tamer</creatorName>
      <givenName>Tamer</givenName>
      <familyName>Uyar</familyName>
      <affiliation>Bilkent Univ, Inst Mat Sci &amp; Nanotechnol, UNAM Natl Nanotechnol Res Ctr, TR-06800 Ankara, Turkey</affiliation>
    </creator>
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  <titles>
    <title>Electrospinning Of Cyclodextrin/Linalool-Inclusion Complex Nanofibers: Fast-Dissolving Nanofibrous Web With Prolonged Release And Antibacterial Activity</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2017</publicationYear>
  <dates>
    <date dateType="Issued">2017-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/49911</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1016/j.foodchem.2017.03.113</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">The volatility and limited water solubility of linalool is a critical issue to be solved. Here, we demonstrated the electrospinning of polymer-free nanofibrous webs of cyclodextrin/linalool-inclusion complex (CD/linalool-IC-NFs). Three types of modified cyclodextrin (HP beta CD, M beta CD, and HP gamma CD) were used to electrospin CD/linalool-IC-NFs. Free-standing CD/linalool-IC-NFs facilitate maximum loading of linalool up to 12% (w/w). A significant amount of linalool (45-89%) was preserved in CD/linalool-IC-NFs, due to enhancement in the thermal stability of linalool by cyclodextrin inclusion complexation. Remarkably, CD/linalool-IC-NFs have shown fast-dissolving characteristics in which these nanofibrous webs dissolved in water within two seconds. Furthermore, linalool release from CD/linalool-IC-NFs inhibited growth of model Gram-negative (E. coli) and Gram-positive (S. aureus) bacteria to a great extent. Briefly, characteristics of liquid linalool have been preserved in a solid nanofiber form and designed CD/linalool-IC-NFs confer high loading capacity, enhanced shelf life and strong antibacterial activity of linalool. (C) 2017 Elsevier Ltd. All rights reserved.</description>
  </descriptions>
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