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Design and In Vitro Evaluation of Bispecific Complexes and Drug Conjugates of Anticancer Peptide, LyP-I in Human Breast Cancer

Timur, Selin Seda; Bhattarai, Prashant; Gursoy, Reyhan Neslihan; Vural, Imran; Khaw, Ban-An


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{
  "@context": "https://schema.org/", 
  "@id": 47829, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Hacettepe Univ, Dept Pharmaceut Technol, Fac Pharm, Ankara, Turkey", 
      "name": "Timur, Selin Seda"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Northeastern Univ, Dept Pharmaceut Sci, Sch Pharm, Bouve Coll Hlth Sci, 360 Huntington Ave, Boston, MA 02115 USA", 
      "name": "Bhattarai, Prashant"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Hacettepe Univ, Dept Pharmaceut Technol, Fac Pharm, Ankara, Turkey", 
      "name": "Gursoy, Reyhan Neslihan"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Hacettepe Univ, Dept Pharmaceut Technol, Fac Pharm, Ankara, Turkey", 
      "name": "Vural, Imran"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Northeastern Univ, Dept Pharmaceut Sci, Sch Pharm, Bouve Coll Hlth Sci, 360 Huntington Ave, Boston, MA 02115 USA", 
      "name": "Khaw, Ban-An"
    }
  ], 
  "datePublished": "2017-01-01", 
  "description": "Purpose LyP-1, a nine-amino-acid tumor homing peptide, selectively binds to its cognate receptor, p32. Overexpression of p32 in certain tumors should allow use of LyP-1 as a targeting agent for the delivery of therapeutic or diagnostic agents. Peptide conjugates are developed for enhanced pretargeting of MDA-MB-231 breast cancer cells with peptideantibody bispecific complexes and targeting with multipledrug/- fluorophore-conjugated nano-polymers.", 
  "headline": "Design and In Vitro Evaluation of Bispecific Complexes and Drug Conjugates of Anticancer Peptide, LyP-I in Human Breast Cancer", 
  "identifier": 47829, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Design and In Vitro Evaluation of Bispecific Complexes and Drug Conjugates of Anticancer Peptide, LyP-I in Human Breast Cancer", 
  "url": "https://aperta.ulakbim.gov.tr/record/47829"
}
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