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Design and In Vitro Evaluation of Bispecific Complexes and Drug Conjugates of Anticancer Peptide, LyP-I in Human Breast Cancer

Timur, Selin Seda; Bhattarai, Prashant; Gursoy, Reyhan Neslihan; Vural, Imran; Khaw, Ban-An


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{
  "DOI": "10.1007/s11095-016-2066-2", 
  "abstract": "Purpose LyP-1, a nine-amino-acid tumor homing peptide, selectively binds to its cognate receptor, p32. Overexpression of p32 in certain tumors should allow use of LyP-1 as a targeting agent for the delivery of therapeutic or diagnostic agents. Peptide conjugates are developed for enhanced pretargeting of MDA-MB-231 breast cancer cells with peptideantibody bispecific complexes and targeting with multipledrug/- fluorophore-conjugated nano-polymers.", 
  "author": [
    {
      "family": "Timur", 
      "given": " Selin Seda"
    }, 
    {
      "family": "Bhattarai", 
      "given": " Prashant"
    }, 
    {
      "family": "Gursoy", 
      "given": " Reyhan Neslihan"
    }, 
    {
      "family": "Vural", 
      "given": " Imran"
    }, 
    {
      "family": "Khaw", 
      "given": " Ban-An"
    }
  ], 
  "container_title": "PHARMACEUTICAL RESEARCH", 
  "id": "47829", 
  "issue": "2", 
  "issued": {
    "date-parts": [
      [
        2017, 
        1, 
        1
      ]
    ]
  }, 
  "page": "352-364", 
  "title": "Design and In Vitro Evaluation of Bispecific Complexes and Drug Conjugates of Anticancer Peptide, LyP-I in Human Breast Cancer", 
  "type": "article-journal", 
  "volume": "34"
}
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