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Turan, Ihsan; Hutchins, B. Ian; Hacihamdioglu, Bulent; Kotan, L. Damla; Gurbuz, Fatih; Ulubay, Ayca; Mengen, Eda; Yuksel, Bilgin; Wray, Susan; Topaloglu, A. Kemal
{ "DOI": "10.1210/jc.2016-3391", "abstract": "Context: Gonadotropin-releasing hormone neurons originate outside the central nervous systemin the olfactory placode and migrate into the central nervous system, becoming integral components of the hypothalamic-pituitary-gonadal axis. Failure of this migration can lead to idiopathic hypogonadotropic hypogonadism (IHH)/Kallmann syndrome (KS). We have previously shown that CCDC141 knockdown leads to impaired migration of GnRH neurons but not of olfactory receptor neurons.", "author": [ { "family": "Turan", "given": " Ihsan" }, { "family": "Hutchins", "given": " B. Ian" }, { "family": "Hacihamdioglu", "given": " Bulent" }, { "family": "Kotan", "given": " L. Damla" }, { "family": "Gurbuz", "given": " Fatih" }, { "family": "Ulubay", "given": " Ayca" }, { "family": "Mengen", "given": " Eda" }, { "family": "Yuksel", "given": " Bilgin" }, { "family": "Wray", "given": " Susan" }, { "family": "Topaloglu", "given": " A. Kemal" } ], "container_title": "JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM", "id": "46747", "issue": "6", "issued": { "date-parts": [ [ 2017, 1, 1 ] ] }, "page": "1816-1825", "title": "CCDC141 Mutations in Idiopathic Hypogonadotropic Hypogonadism", "type": "article-journal", "volume": "102" }
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