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Genome-wide analysis of endogenously expressed ZEB2 binding sites reveals inverse correlations between ZEB2 and GalNAc-transferase GALNT3 in human tumors

Balcik-Ercin, Pelin; Cetin, Metin; Yalim-Camci, Irem; Odabas, Gorkem; Tokay, Nurettin; Sayan, A. Emre; Yagci, Tamer


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{
  "@context": "https://schema.org/", 
  "@id": 36631, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Gebze Tech Univ, Dept Mol Biol & Genet, Mol Oncol Lab, C2 Bldg, TR-41400 Gebze, Turkey", 
      "name": "Balcik-Ercin, Pelin"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Gebze Tech Univ, Dept Mol Biol & Genet, Mol Oncol Lab, C2 Bldg, TR-41400 Gebze, Turkey", 
      "name": "Cetin, Metin"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Gebze Tech Univ, Dept Mol Biol & Genet, Mol Oncol Lab, C2 Bldg, TR-41400 Gebze, Turkey", 
      "name": "Yalim-Camci, Irem"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Gebze Tech Univ, Dept Mol Biol & Genet, Mol Oncol Lab, C2 Bldg, TR-41400 Gebze, Turkey", 
      "name": "Odabas, Gorkem"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Gebze Tech Univ, Dept Mol Biol & Genet, Mol Oncol Lab, C2 Bldg, TR-41400 Gebze, Turkey", 
      "name": "Tokay, Nurettin"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Univ Southampton, Canc Sci, Fac Med, Somers Bldg,Tremona Rd, Southampton SO16 6YD, Hants, England", 
      "name": "Sayan, A. Emre"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Gebze Tech Univ, Dept Mol Biol & Genet, Mol Oncol Lab, C2 Bldg, TR-41400 Gebze, Turkey", 
      "name": "Yagci, Tamer"
    }
  ], 
  "datePublished": "2018-01-01", 
  "description": "ZEB2 is a transcriptional repressor that regulates epithelial-to-mesenchymal transition (EMT) through binding to bipartite E-box motifs in gene regulatory regions. Despite the abundant presence of E-boxes within the human genome and the multiplicity of pathophysiological processes regulated during ZEB2-induced EMT, only a small fraction of ZEB2 targets has been identified so far. Hence, we explored genome-wide ZEB2 binding by chromatin immunoprecipitation-sequencing (ChIP-seq) under endogenous ZEB2 expression conditions.", 
  "headline": "Genome-wide analysis of endogenously expressed ZEB2 binding sites reveals inverse correlations between ZEB2 and GalNAc-transferase GALNT3 in human tumors", 
  "identifier": 36631, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Genome-wide analysis of endogenously expressed ZEB2 binding sites reveals inverse correlations between ZEB2 and GalNAc-transferase GALNT3 in human tumors", 
  "url": "https://aperta.ulakbim.gov.tr/record/36631"
}
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