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Genome-wide analysis of endogenously expressed ZEB2 binding sites reveals inverse correlations between ZEB2 and GalNAc-transferase GALNT3 in human tumors

Balcik-Ercin, Pelin; Cetin, Metin; Yalim-Camci, Irem; Odabas, Gorkem; Tokay, Nurettin; Sayan, A. Emre; Yagci, Tamer


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{
  "DOI": "10.1007/s13402-018-0375-7", 
  "abstract": "ZEB2 is a transcriptional repressor that regulates epithelial-to-mesenchymal transition (EMT) through binding to bipartite E-box motifs in gene regulatory regions. Despite the abundant presence of E-boxes within the human genome and the multiplicity of pathophysiological processes regulated during ZEB2-induced EMT, only a small fraction of ZEB2 targets has been identified so far. Hence, we explored genome-wide ZEB2 binding by chromatin immunoprecipitation-sequencing (ChIP-seq) under endogenous ZEB2 expression conditions.", 
  "author": [
    {
      "family": "Balcik-Ercin", 
      "given": " Pelin"
    }, 
    {
      "family": "Cetin", 
      "given": " Metin"
    }, 
    {
      "family": "Yalim-Camci", 
      "given": " Irem"
    }, 
    {
      "family": "Odabas", 
      "given": " Gorkem"
    }, 
    {
      "family": "Tokay", 
      "given": " Nurettin"
    }, 
    {
      "family": "Sayan", 
      "given": " A. Emre"
    }, 
    {
      "family": "Yagci", 
      "given": " Tamer"
    }
  ], 
  "container_title": "CELLULAR ONCOLOGY", 
  "id": "36631", 
  "issue": "4", 
  "issued": {
    "date-parts": [
      [
        2018, 
        1, 
        1
      ]
    ]
  }, 
  "page": "379-393", 
  "title": "Genome-wide analysis of endogenously expressed ZEB2 binding sites reveals inverse correlations between ZEB2 and GalNAc-transferase GALNT3 in human tumors", 
  "type": "article-journal", 
  "volume": "41"
}
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