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Resolution of (+/-)-beta-Methylphenylethylamine by a Novel Chiral Stationary Phase for Pirkle-Type Column Chromatography

Yilmaz, Hayrullah; Topal, Giray; Cakmak, Resit; Hosgoren, Halil


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{
  "DOI": "10.1002/chir.20736", 
  "abstract": "In this study, a new Pirkle-type chiral column stationary phase for resolution of beta-methylphenylethyl amine was described by using activated Sepharose 4B as a matrix, L-tyrosine as a spacer arm, and an aromatic amine derivative of L-glutamic acid as a ligand. The binding capacities of the stationary phase were determined at different pH values (pH = 6, 7, and 8) using buffer solutions as mobile phase, and enantiomeric excess (ee) was determined by HPLC equipped with chiral column. The ee was found to be 47%. Chirality 22:252-257, 2010. (C) 2009 Wiley-Liss, Inc.", 
  "author": [
    {
      "family": "Yilmaz", 
      "given": " Hayrullah"
    }, 
    {
      "family": "Topal", 
      "given": " Giray"
    }, 
    {
      "family": "Cakmak", 
      "given": " Resit"
    }, 
    {
      "family": "Hosgoren", 
      "given": " Halil"
    }
  ], 
  "container_title": "CHIRALITY", 
  "id": "26825", 
  "issue": "2", 
  "issued": {
    "date-parts": [
      [
        2010, 
        1, 
        1
      ]
    ]
  }, 
  "page": "252-257", 
  "title": "Resolution of (+/-)-beta-Methylphenylethylamine by a Novel Chiral Stationary Phase for Pirkle-Type Column Chromatography", 
  "type": "article-journal", 
  "volume": "22"
}
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