1 Ocak 2022 Dergi makalesi Açık Erişim

Zhang, Yun; Donaher, Joana Liu; Das, Sunny; Li, Xin; Reinhardt, Ferenc; Krall, Jordan A.; Lambert, Arthur W.; Thiru, Prathapan; Keys, Heather R.; Khan, Mehreen; Hofree, Matan; Wilson, Molly M.; Yedier-Bayram, Ozlem; Lack, Nathan A.; Onder, Tamer T.; Bagci-Onder, Tugba; Tyler, Michael; Tirosh, Itay; Regev, Aviv; Lees, Jacqueline A.; Lees, Jacqueline A.

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/259629</identifier>
  <creators>
    <creator>
      <creatorName>Zhang, Yun</creatorName>
      <givenName>Yun</givenName>
      <familyName>Zhang</familyName>
      <affiliation>Whitehead Inst Biomed Res, 9 Cambridge Ctr, Cambridge, MA 02142 USA</affiliation>
    </creator>
    <creator>
      <creatorName>Donaher, Joana Liu</creatorName>
      <givenName>Joana Liu</givenName>
      <familyName>Donaher</familyName>
      <affiliation>Whitehead Inst Biomed Res, 9 Cambridge Ctr, Cambridge, MA 02142 USA</affiliation>
    </creator>
    <creator>
      <creatorName>Das, Sunny</creatorName>
      <givenName>Sunny</givenName>
      <familyName>Das</familyName>
      <affiliation>Whitehead Inst Biomed Res, 9 Cambridge Ctr, Cambridge, MA 02142 USA</affiliation>
    </creator>
    <creator>
      <creatorName>Li, Xin</creatorName>
      <givenName>Xin</givenName>
      <familyName>Li</familyName>
      <affiliation>Whitehead Inst Biomed Res, 9 Cambridge Ctr, Cambridge, MA 02142 USA</affiliation>
    </creator>
    <creator>
      <creatorName>Reinhardt, Ferenc</creatorName>
      <givenName>Ferenc</givenName>
      <familyName>Reinhardt</familyName>
      <affiliation>Whitehead Inst Biomed Res, 9 Cambridge Ctr, Cambridge, MA 02142 USA</affiliation>
    </creator>
    <creator>
      <creatorName>Krall, Jordan A.</creatorName>
      <givenName>Jordan A.</givenName>
      <familyName>Krall</familyName>
      <affiliation>Whitehead Inst Biomed Res, 9 Cambridge Ctr, Cambridge, MA 02142 USA</affiliation>
    </creator>
    <creator>
      <creatorName>Lambert, Arthur W.</creatorName>
      <givenName>Arthur W.</givenName>
      <familyName>Lambert</familyName>
      <affiliation>Whitehead Inst Biomed Res, 9 Cambridge Ctr, Cambridge, MA 02142 USA</affiliation>
    </creator>
    <creator>
      <creatorName>Thiru, Prathapan</creatorName>
      <givenName>Prathapan</givenName>
      <familyName>Thiru</familyName>
      <affiliation>Whitehead Inst Biomed Res, 9 Cambridge Ctr, Cambridge, MA 02142 USA</affiliation>
    </creator>
    <creator>
      <creatorName>Keys, Heather R.</creatorName>
      <givenName>Heather R.</givenName>
      <familyName>Keys</familyName>
      <affiliation>Whitehead Inst Biomed Res, 9 Cambridge Ctr, Cambridge, MA 02142 USA</affiliation>
    </creator>
    <creator>
      <creatorName>Khan, Mehreen</creatorName>
      <givenName>Mehreen</givenName>
      <familyName>Khan</familyName>
      <affiliation>Whitehead Inst Biomed Res, 9 Cambridge Ctr, Cambridge, MA 02142 USA</affiliation>
    </creator>
    <creator>
      <creatorName>Hofree, Matan</creatorName>
      <givenName>Matan</givenName>
      <familyName>Hofree</familyName>
      <affiliation>Broad Inst MIT &amp; Harvard, Klarman Cell Observ, Cambridge, MA 02142 USA</affiliation>
    </creator>
    <creator>
      <creatorName>Wilson, Molly M.</creatorName>
      <givenName>Molly M.</givenName>
      <familyName>Wilson</familyName>
    </creator>
    <creator>
      <creatorName>Yedier-Bayram, Ozlem</creatorName>
      <givenName>Ozlem</givenName>
      <familyName>Yedier-Bayram</familyName>
      <affiliation>Koc Univ, Sch Med, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Lack, Nathan A.</creatorName>
      <givenName>Nathan A.</givenName>
      <familyName>Lack</familyName>
    </creator>
    <creator>
      <creatorName>Onder, Tamer T.</creatorName>
      <givenName>Tamer T.</givenName>
      <familyName>Onder</familyName>
      <affiliation>Koc Univ, Sch Med, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Bagci-Onder, Tugba</creatorName>
      <givenName>Tugba</givenName>
      <familyName>Bagci-Onder</familyName>
      <affiliation>Koc Univ, Sch Med, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Tyler, Michael</creatorName>
      <givenName>Michael</givenName>
      <familyName>Tyler</familyName>
      <affiliation>Weizmann Inst Sci, Dept Mol Cell Biol, Rehovot, Israel</affiliation>
    </creator>
    <creator>
      <creatorName>Tirosh, Itay</creatorName>
      <givenName>Itay</givenName>
      <familyName>Tirosh</familyName>
      <affiliation>Weizmann Inst Sci, Dept Mol Cell Biol, Rehovot, Israel</affiliation>
    </creator>
    <creator>
      <creatorName>Regev, Aviv</creatorName>
      <givenName>Aviv</givenName>
      <familyName>Regev</familyName>
    </creator>
    <creator>
      <creatorName>Lees, Jacqueline A.</creatorName>
      <givenName>Jacqueline A.</givenName>
      <familyName>Lees</familyName>
    </creator>
    <creator>
      <creatorName>Lees, Jacqueline A.</creatorName>
      <givenName>Jacqueline A.</givenName>
      <familyName>Lees</familyName>
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  <titles>
    <title>Genome-Wide Crispr Screen Identifies Prc2 And Kmt2D-Compass As Regulators Of Distinct Emt Trajectories That Contribute Differentially To Metastasis</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2022</publicationYear>
  <dates>
    <date dateType="Issued">2022-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/259629</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1038/s41556-022-00877-0</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Through genome-wide and focused CRISPR screens, Zhang et al. discover that loss of PRC2 or KMT2D-COMPASS enables distinct EMT trajectories, which exert differential effects on the metastatic capability of carcinoma cells.</description>
  </descriptions>
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