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Effect of dietary nano-selenium on stress indicators, immune response, and DNA damage in broiler subjected to different stocking density

Sevim, O.; Ahsan, U.; Tatli, O.; Kuter, E.; Khamseh, E. Karimiyan; Temiz, A. Reman; Ozdemir, O. Sayin; Aydin, A. K.; Sahiner, H. S.; Avcioglu, M.; Yildirim, E. Koc


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  <dc:creator>Sevim, O.</dc:creator>
  <dc:creator>Ahsan, U.</dc:creator>
  <dc:creator>Tatli, O.</dc:creator>
  <dc:creator>Kuter, E.</dc:creator>
  <dc:creator>Khamseh, E. Karimiyan</dc:creator>
  <dc:creator>Temiz, A. Reman</dc:creator>
  <dc:creator>Ozdemir, O. Sayin</dc:creator>
  <dc:creator>Aydin, A. K.</dc:creator>
  <dc:creator>Sahiner, H. S.</dc:creator>
  <dc:creator>Avcioglu, M.</dc:creator>
  <dc:creator>Yildirim, E. Koc</dc:creator>
  <dc:date>2021-01-01</dc:date>
  <dc:description>In the present study, we examined the effect of nano-selenium (nano-Se) and stocking density (SD) on antioxidant status, immune response, and DNA damage in broiler chickens. A total of 480 one-d-old male broilers (Ross 308) were randomly divided into 4 treatments each including 8 replicates for 42 days. A 2 x 2 factorial arrangement of groups for two dietary selenium forms (inorganic or nano) and two stocking densities [low = 12 birds/m(2) (LSD) and high = 18 birds/m(2) (HSD)] was conducted. Starter, grower, and finisher diets were formulated based on corn-soybean meal according to recommendations of Aviagen. There were no significant differences in the lymphoid organ index due to high stocking density or nano-Se. Neither HSD nor dietary nano-Se had an effect on blood heterophil: lymphocyte ratio, serum corticosterone, glutathione, superoxide dismutase, and malondialdehyde levels. Serum interferon-gamma, interleukin 12, and interleukin 18 levels were not affected either by HSD or by dietary nano-Se. However, an interaction was witnessed between SD and dietary Se form for serum interferon-gamma (P &lt; 0.05). HSD increased the DNA damage in lymphocyte (P &lt; 0.05), but dietary nano-Se had no significant effect on it. In conclusion, HSD and dietary nano-Se may not affect the organ index, stress indicators, and immune function, but dietary nano-Se decreased the possible negative effect of HSD on serum interferon-gamma. HSD increased the DNA damage but dietary nano-Se had no effect.</dc:description>
  <dc:identifier>https://aperta.ulakbim.gov.trrecord/235110</dc:identifier>
  <dc:identifier>oai:aperta.ulakbim.gov.tr:235110</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://www.opendefinition.org/licenses/cc-by</dc:rights>
  <dc:source>EUROPEAN POULTRY SCIENCE 85 1-13</dc:source>
  <dc:title>Effect of dietary nano-selenium on stress indicators, immune response, and DNA damage in broiler subjected to different stocking density</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
</oai_dc:dc>
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