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Effect of dietary nano-selenium on stress indicators, immune response, and DNA damage in broiler subjected to different stocking density

Sevim, O.; Ahsan, U.; Tatli, O.; Kuter, E.; Khamseh, E. Karimiyan; Temiz, A. Reman; Ozdemir, O. Sayin; Aydin, A. K.; Sahiner, H. S.; Avcioglu, M.; Yildirim, E. Koc


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{
  "@context": "https://schema.org/", 
  "@id": 235110, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Adnan Menderes Univ, Fac Vet Med, Dept Anim Nutr & Nutr Dis, TR-09016 Aydin, Turkey", 
      "name": "Sevim, O."
    }, 
    {
      "@type": "Person", 
      "affiliation": "Burdur Mehmet Akif Ersoy Univ, Dept Plant & Anim Prod, Burdur Vocat Sch Food Agr & Livestock, Istiklal Campus, TR-15030 Burdur, Turkey", 
      "name": "Ahsan, U."
    }, 
    {
      "@type": "Person", 
      "affiliation": "Adnan Menderes Univ, Fac Vet Med, Dept Anim Nutr & Nutr Dis, TR-09016 Aydin, Turkey", 
      "name": "Tatli, O."
    }, 
    {
      "@type": "Person", 
      "affiliation": "Burdur Mehmet Akif Ersoy Univ, Fac Vet Med, Dept Anim Nutr & Nutr Dis, Istiklal Campus, TR-15030 Burdur, Turkey", 
      "name": "Kuter, E."
    }, 
    {
      "@type": "Person", 
      "affiliation": "Adnan Menderes Univ, Fac Vet Med, Dept Anim Nutr & Nutr Dis, TR-09016 Aydin, Turkey", 
      "name": "Khamseh, E. Karimiyan"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Adnan Menderes Univ, Fac Vet Med, Dept Anim Nutr & Nutr Dis, TR-09016 Aydin, Turkey", 
      "name": "Temiz, A. Reman"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Adnan Menderes Univ, Fac Vet Med, Dept Anim Nutr & Nutr Dis, TR-09016 Aydin, Turkey", 
      "name": "Ozdemir, O. Sayin"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Adnan Menderes Univ, Fac Vet Med, Dept Anim Nutr & Nutr Dis, TR-09016 Aydin, Turkey", 
      "name": "Aydin, A. K."
    }, 
    {
      "@type": "Person", 
      "affiliation": "Adnan Menderes Univ, Fac Vet Med, Dept Pharmacol & Toxicol, TR-09016 Aydin, Turkey", 
      "name": "Sahiner, H. S."
    }, 
    {
      "@type": "Person", 
      "affiliation": "Adnan Menderes Univ, Fac Vet Med, Dept Pharmacol & Toxicol, TR-09016 Aydin, Turkey", 
      "name": "Avcioglu, M."
    }, 
    {
      "@type": "Person", 
      "affiliation": "Adnan Menderes Univ, Fac Vet Med, Dept Physiol, TR-09016 Aydin, Turkey", 
      "name": "Yildirim, E. Koc"
    }
  ], 
  "datePublished": "2021-01-01", 
  "description": "In the present study, we examined the effect of nano-selenium (nano-Se) and stocking density (SD) on antioxidant status, immune response, and DNA damage in broiler chickens. A total of 480 one-d-old male broilers (Ross 308) were randomly divided into 4 treatments each including 8 replicates for 42 days. A 2 x 2 factorial arrangement of groups for two dietary selenium forms (inorganic or nano) and two stocking densities [low = 12 birds/m(2) (LSD) and high = 18 birds/m(2) (HSD)] was conducted. Starter, grower, and finisher diets were formulated based on corn-soybean meal according to recommendations of Aviagen. There were no significant differences in the lymphoid organ index due to high stocking density or nano-Se. Neither HSD nor dietary nano-Se had an effect on blood heterophil: lymphocyte ratio, serum corticosterone, glutathione, superoxide dismutase, and malondialdehyde levels. Serum interferon-gamma, interleukin 12, and interleukin 18 levels were not affected either by HSD or by dietary nano-Se. However, an interaction was witnessed between SD and dietary Se form for serum interferon-gamma (P < 0.05). HSD increased the DNA damage in lymphocyte (P < 0.05), but dietary nano-Se had no significant effect on it. In conclusion, HSD and dietary nano-Se may not affect the organ index, stress indicators, and immune function, but dietary nano-Se decreased the possible negative effect of HSD on serum interferon-gamma. HSD increased the DNA damage but dietary nano-Se had no effect.", 
  "headline": "Effect of dietary nano-selenium on stress indicators, immune response, and DNA damage in broiler subjected to different stocking density", 
  "identifier": 235110, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Effect of dietary nano-selenium on stress indicators, immune response, and DNA damage in broiler subjected to different stocking density", 
  "url": "https://aperta.ulakbim.gov.tr/record/235110"
}
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