1 Ocak 2021 Dergi makalesi Açık Erişim

Sevim, O.; Ahsan, U.; Tatli, O.; Kuter, E.; Khamseh, E. Karimiyan; Temiz, A. Reman; Ozdemir, O. Sayin; Aydin, A. K.; Sahiner, H. S.; Avcioglu, M.; Yildirim, E. Koc

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{
  "DOI": "10.1399/eps.2021.345", 
  "abstract": "In the present study, we examined the effect of nano-selenium (nano-Se) and stocking density (SD) on antioxidant status, immune response, and DNA damage in broiler chickens. A total of 480 one-d-old male broilers (Ross 308) were randomly divided into 4 treatments each including 8 replicates for 42 days. A 2 x 2 factorial arrangement of groups for two dietary selenium forms (inorganic or nano) and two stocking densities [low = 12 birds/m(2) (LSD) and high = 18 birds/m(2) (HSD)] was conducted. Starter, grower, and finisher diets were formulated based on corn-soybean meal according to recommendations of Aviagen. There were no significant differences in the lymphoid organ index due to high stocking density or nano-Se. Neither HSD nor dietary nano-Se had an effect on blood heterophil: lymphocyte ratio, serum corticosterone, glutathione, superoxide dismutase, and malondialdehyde levels. Serum interferon-gamma, interleukin 12, and interleukin 18 levels were not affected either by HSD or by dietary nano-Se. However, an interaction was witnessed between SD and dietary Se form for serum interferon-gamma (P < 0.05). HSD increased the DNA damage in lymphocyte (P < 0.05), but dietary nano-Se had no significant effect on it. In conclusion, HSD and dietary nano-Se may not affect the organ index, stress indicators, and immune function, but dietary nano-Se decreased the possible negative effect of HSD on serum interferon-gamma. HSD increased the DNA damage but dietary nano-Se had no effect.", 
  "author": [
    {
      "family": "Sevim", 
      "given": " O."
    }, 
    {
      "family": "Ahsan", 
      "given": " U."
    }, 
    {
      "family": "Tatli", 
      "given": " O."
    }, 
    {
      "family": "Kuter", 
      "given": " E."
    }, 
    {
      "family": "Khamseh", 
      "given": " E. Karimiyan"
    }, 
    {
      "family": "Temiz", 
      "given": " A. Reman"
    }, 
    {
      "family": "Ozdemir", 
      "given": " O. Sayin"
    }, 
    {
      "family": "Aydin", 
      "given": " A. K."
    }, 
    {
      "family": "Sahiner", 
      "given": " H. S."
    }, 
    {
      "family": "Avcioglu", 
      "given": " M."
    }, 
    {
      "family": "Yildirim", 
      "given": " E. Koc"
    }
  ], 
  "container_title": "EUROPEAN POULTRY SCIENCE", 
  "id": "235110", 
  "issued": {
    "date-parts": [
      [
        2021, 
        1, 
        1
      ]
    ]
  }, 
  "page": "1-13", 
  "title": "Effect of dietary nano-selenium on stress indicators, immune response, and DNA damage in broiler subjected to different stocking density", 
  "type": "article-journal", 
  "volume": "85"
}