1 Ocak 2022 Dergi makalesi Açık Erişim

Cakmak, Soner

Dublin Core

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  <dc:creator>Cakmak, Soner</dc:creator>
  <dc:date>2022-01-01</dc:date>
  <dc:description>In this study, amorphous hydroxyapatite (am-HAp) incorporated compressible and nanofibrous polyglycolic acid (PGA-HAp) matrices were fabricated by three-dimensional (3-D) electrospinning. The synthesised am-HAp particles were in the size of 260 +/- 45 nm. X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) analyses confirmed the chemical and phase structure of the am-HAp particles. Continuous PGA-HAp nanofibers with the mean diameter of 367 +/- 70 nm were successfully produced and am-HAp particles were well integrated into the nanofibers. Moreover, XRD and FTIR analyses verified the presence of am-HAp in the PGA nanofibers. The incorporation of the am-HAp to the nanofibers increased the maximum degradation temperature of PGA matrices from 340 degrees C to 362 degrees C. Mechanical analyses confirmed the elasticity of the 3-D PGA matrices. In vitro cell culture studies verified the biocompatibility of the nanofibrous matrices. Hence, 3-D nanofibrous PGA-HAp matrices may be a good alternative to ceramic bone substitutes due to their flexibility and physicochemical properties.</dc:description>
  <dc:identifier>https://aperta.ulakbim.gov.trrecord/233012</dc:identifier>
  <dc:identifier>oai:aperta.ulakbim.gov.tr:233012</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://www.opendefinition.org/licenses/cc-by</dc:rights>
  <dc:source>MATERIALS TECHNOLOGY 37(1) 9-20</dc:source>
  <dc:title>Compressible polyglycolic acid-based nanofibrous matrices as a bone filler: fabrication, physicochemical characterisations, and biocompatibility evaluation</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
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