1 Ocak 2022 Dergi makalesi Açık Erişim

Cakmak, Soner

Citation Style Language JSON

{
  "DOI": "10.1080/10667857.2021.1959216", 
  "abstract": "In this study, amorphous hydroxyapatite (am-HAp) incorporated compressible and nanofibrous polyglycolic acid (PGA-HAp) matrices were fabricated by three-dimensional (3-D) electrospinning. The synthesised am-HAp particles were in the size of 260 +/- 45 nm. X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) analyses confirmed the chemical and phase structure of the am-HAp particles. Continuous PGA-HAp nanofibers with the mean diameter of 367 +/- 70 nm were successfully produced and am-HAp particles were well integrated into the nanofibers. Moreover, XRD and FTIR analyses verified the presence of am-HAp in the PGA nanofibers. The incorporation of the am-HAp to the nanofibers increased the maximum degradation temperature of PGA matrices from 340 degrees C to 362 degrees C. Mechanical analyses confirmed the elasticity of the 3-D PGA matrices. In vitro cell culture studies verified the biocompatibility of the nanofibrous matrices. Hence, 3-D nanofibrous PGA-HAp matrices may be a good alternative to ceramic bone substitutes due to their flexibility and physicochemical properties.", 
  "author": [
    {
      "family": "Cakmak", 
      "given": " Soner"
    }
  ], 
  "container_title": "MATERIALS TECHNOLOGY", 
  "id": "233012", 
  "issue": "1", 
  "issued": {
    "date-parts": [
      [
        2022, 
        1, 
        1
      ]
    ]
  }, 
  "page": "9-20", 
  "title": "Compressible polyglycolic acid-based nanofibrous matrices as a bone filler: fabrication, physicochemical characterisations, and biocompatibility evaluation", 
  "type": "article-journal", 
  "volume": "37"
}