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Supercritical carbon dioxide extraction of Usnea longissima (L.) Ach.: Optimization by Box-Behnken design (BBD)

Atila Dincer, Ceren; Gokalp, Ceren; Getiren, Bengu; Yildiz, Atila; Yildiz, Nuray


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{
  "@context": "https://schema.org/", 
  "@id": 230266, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Ankara Univ, Fac Engn, Dept Chem Engn, Ankara, Turkey", 
      "name": "Atila Dincer, Ceren"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ankara Univ, Fac Engn, Dept Chem Engn, Ankara, Turkey", 
      "name": "Gokalp, Ceren"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ankara Univ, Fac Engn, Dept Chem Engn, Ankara, Turkey", 
      "name": "Getiren, Bengu"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ankara Univ, Dept Biol, Ankara, Turkey", 
      "name": "Yildiz, Atila"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ankara Univ, Fac Engn, Dept Chem Engn, Ankara, Turkey", 
      "name": "Yildiz, Nuray"
    }
  ], 
  "datePublished": "2021-01-01", 
  "description": "Usnic acid (UA) was extracted from Usnea longissima (L.) Ach. in supercritical carbon dioxide (SC-CO2) medium. The selected process parameters were extraction temperature (35-45 degrees C), amount of co-solvent (0%-5%) and extraction time (5-9 h). These parameters were applied to Box-Behnken design (BBD) belonging to response surface methodology (RSM) to determine optimum process parameters for the highest amount of UA in the extract. g UA/100g lichen, extraction yield % and UA content values were calculated in the range of 0.045-0.317, 2.77-5.4 and 71%-82% in different experimental conditions, respectively. The optimum conditions were predicted as 42 degrees C, 4.3% (ethanol) and 7.48 h. It was determined that the predicted and experimental values of g UA/100g lichen were compatible, and the suggested model was valid.", 
  "headline": "Supercritical carbon dioxide extraction of Usnea longissima (L.) Ach.: Optimization by Box-Behnken design (BBD)", 
  "identifier": 230266, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Supercritical carbon dioxide extraction of Usnea longissima (L.) Ach.: Optimization by Box-Behnken design (BBD)", 
  "url": "https://aperta.ulakbim.gov.tr/record/230266"
}
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