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Atila Dincer, Ceren; Gokalp, Ceren; Getiren, Bengu; Yildiz, Atila; Yildiz, Nuray
{ "DOI": "10.3906/kim-2102-66", "abstract": "Usnic acid (UA) was extracted from Usnea longissima (L.) Ach. in supercritical carbon dioxide (SC-CO2) medium. The selected process parameters were extraction temperature (35-45 degrees C), amount of co-solvent (0%-5%) and extraction time (5-9 h). These parameters were applied to Box-Behnken design (BBD) belonging to response surface methodology (RSM) to determine optimum process parameters for the highest amount of UA in the extract. g UA/100g lichen, extraction yield % and UA content values were calculated in the range of 0.045-0.317, 2.77-5.4 and 71%-82% in different experimental conditions, respectively. The optimum conditions were predicted as 42 degrees C, 4.3% (ethanol) and 7.48 h. It was determined that the predicted and experimental values of g UA/100g lichen were compatible, and the suggested model was valid.", "author": [ { "family": "Atila Dincer", "given": " Ceren" }, { "family": "Gokalp", "given": " Ceren" }, { "family": "Getiren", "given": " Bengu" }, { "family": "Yildiz", "given": " Atila" }, { "family": "Yildiz", "given": " Nuray" } ], "container_title": "TURKISH JOURNAL OF CHEMISTRY", "id": "230266", "issue": "4", "issued": { "date-parts": [ [ 2021, 1, 1 ] ] }, "page": "1248-1256", "title": "Supercritical carbon dioxide extraction of Usnea longissima (L.) Ach.: Optimization by Box-Behnken design (BBD)", "type": "article-journal", "volume": "45" }
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