1 Ocak 2021 Dergi makalesi Açık Erişim

Atila Dincer, Ceren; Gokalp, Ceren; Getiren, Bengu; Yildiz, Atila; Yildiz, Nuray

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    "creators": [
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        "affiliation": "Ankara Univ, Fac Engn, Dept Chem Engn, Ankara, Turkey", 
        "name": "Atila Dincer, Ceren"
      }, 
      {
        "affiliation": "Ankara Univ, Fac Engn, Dept Chem Engn, Ankara, Turkey", 
        "name": "Gokalp, Ceren"
      }, 
      {
        "affiliation": "Ankara Univ, Fac Engn, Dept Chem Engn, Ankara, Turkey", 
        "name": "Getiren, Bengu"
      }, 
      {
        "affiliation": "Ankara Univ, Dept Biol, Ankara, Turkey", 
        "name": "Yildiz, Atila"
      }, 
      {
        "affiliation": "Ankara Univ, Fac Engn, Dept Chem Engn, Ankara, Turkey", 
        "name": "Yildiz, Nuray"
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    "description": "Usnic acid (UA) was extracted from Usnea longissima (L.) Ach. in supercritical carbon dioxide (SC-CO2) medium. The selected process parameters were extraction temperature (35-45 degrees C), amount of co-solvent (0%-5%) and extraction time (5-9 h). These parameters were applied to Box-Behnken design (BBD) belonging to response surface methodology (RSM) to determine optimum process parameters for the highest amount of UA in the extract. g UA/100g lichen, extraction yield % and UA content values were calculated in the range of 0.045-0.317, 2.77-5.4 and 71%-82% in different experimental conditions, respectively. The optimum conditions were predicted as 42 degrees C, 4.3% (ethanol) and 7.48 h. It was determined that the predicted and experimental values of g UA/100g lichen were compatible, and the suggested model was valid.", 
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      "issue": "4", 
      "pages": "1248-1256", 
      "title": "TURKISH JOURNAL OF CHEMISTRY", 
      "volume": "45"
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    "publication_date": "2021-01-01", 
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    "title": "Supercritical carbon dioxide extraction of Usnea longissima (L.) Ach.: Optimization by Box-Behnken design (BBD)"
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