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Supercritical carbon dioxide extraction of Usnea longissima (L.) Ach.: Optimization by Box-Behnken design (BBD)

Atila Dincer, Ceren; Gokalp, Ceren; Getiren, Bengu; Yildiz, Atila; Yildiz, Nuray


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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/230266</identifier>
  <creators>
    <creator>
      <creatorName>Atila Dincer, Ceren</creatorName>
      <givenName>Ceren</givenName>
      <familyName>Atila Dincer</familyName>
      <affiliation>Ankara Univ, Fac Engn, Dept Chem Engn, Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Gokalp, Ceren</creatorName>
      <givenName>Ceren</givenName>
      <familyName>Gokalp</familyName>
      <affiliation>Ankara Univ, Fac Engn, Dept Chem Engn, Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Getiren, Bengu</creatorName>
      <givenName>Bengu</givenName>
      <familyName>Getiren</familyName>
      <affiliation>Ankara Univ, Fac Engn, Dept Chem Engn, Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Yildiz, Atila</creatorName>
      <givenName>Atila</givenName>
      <familyName>Yildiz</familyName>
      <affiliation>Ankara Univ, Dept Biol, Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Yildiz, Nuray</creatorName>
      <givenName>Nuray</givenName>
      <familyName>Yildiz</familyName>
      <affiliation>Ankara Univ, Fac Engn, Dept Chem Engn, Ankara, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Supercritical Carbon Dioxide Extraction Of Usnea Longissima (L.) Ach.: Optimization By Box-Behnken Design (Bbd)</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2021</publicationYear>
  <dates>
    <date dateType="Issued">2021-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/230266</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.3906/kim-2102-66</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Usnic acid (UA) was extracted from Usnea longissima (L.) Ach. in supercritical carbon dioxide (SC-CO2) medium. The selected process parameters were extraction temperature (35-45 degrees C), amount of co-solvent (0%-5%) and extraction time (5-9 h). These parameters were applied to Box-Behnken design (BBD) belonging to response surface methodology (RSM) to determine optimum process parameters for the highest amount of UA in the extract. g UA/100g lichen, extraction yield % and UA content values were calculated in the range of 0.045-0.317, 2.77-5.4 and 71%-82% in different experimental conditions, respectively. The optimum conditions were predicted as 42 degrees C, 4.3% (ethanol) and 7.48 h. It was determined that the predicted and experimental values of g UA/100g lichen were compatible, and the suggested model was valid.</description>
  </descriptions>
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