Dergi makalesi Açık Erişim
Calik, Pinar; Bozkurt, Bahar; Zerze, Gul H.; Inankur, Bahar; Bayraktar, Eda; Boy, Erdem; Orman, Mehmet Ali; Acik, Eda; Ozdamar, Tuncer H.
{ "DOI": "10.1002/jctb.4011", "abstract": "BACKGROUNDEffects of co-substrate sorbitol different feeding strategies on recombinant human growth hormone (rhGH) production by Pichia pastoris hGH-Mut(+) were investigated by eight designed experiments grouped as: (i) fed-batch methanol feeding without the co-substrate; (ii) fed-batch methanol feeding with pulse sorbitol feeding; (iii) fed-batch methanol feeding together with fed-batch sorbitol feeding at t=0-15h, followed by fed-batch methanol feeding; and (iv) fed-batch methanol and sorbitol feeding at t=0-30h, followed with fed-batch methanol feeding.", "author": [ { "family": "Calik", "given": " Pinar" }, { "family": "Bozkurt", "given": " Bahar" }, { "family": "Zerze", "given": " Gul H." }, { "family": "Inankur", "given": " Bahar" }, { "family": "Bayraktar", "given": " Eda" }, { "family": "Boy", "given": " Erdem" }, { "family": "Orman", "given": " Mehmet Ali" }, { "family": "Acik", "given": " Eda" }, { "family": "Ozdamar", "given": " Tuncer H." } ], "container_title": "JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY", "id": "17743", "issue": "9", "issued": { "date-parts": [ [ 2013, 1, 1 ] ] }, "page": "1631-1640", "title": "Effect of co-substrate sorbitol different feeding strategies on human growth hormone production by recombinant Pichia pastoris", "type": "article-journal", "volume": "88" }
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