1 Ocak 2019 Dergi makalesi Açık Erişim

Sezer, Umran Aydemir; Sahin, Isa; Aru, Basak; Olmez, Hulya; Demirel, Gulderen Yanikkaya; Sezer, Serdar

MARC21 XML

<?xml version='1.0' encoding='UTF-8'?>
<record xmlns="http://www.loc.gov/MARC21/slim">
  <leader>00000nam##2200000uu#4500</leader>
  <datafield tag="245" ind1=" " ind2=" ">
    <subfield code="a">Cytotoxicity, bactericidal and hemostatic evaluation of oxidized cellulose microparticles: Structure and oxidation degree approach</subfield>
  </datafield>
  <datafield tag="909" ind1="C" ind2="4">
    <subfield code="p">CARBOHYDRATE POLYMERS</subfield>
    <subfield code="v">219</subfield>
    <subfield code="c">87-94</subfield>
  </datafield>
  <controlfield tag="001">99881</controlfield>
  <datafield tag="980" ind1=" " ind2=" ">
    <subfield code="a">user-tubitak-adresli-yayinlar</subfield>
  </datafield>
  <datafield tag="520" ind1=" " ind2=" ">
    <subfield code="a">Oxidized cellulose is the most used hemostatic materials in clinical applications. In addition to its perfect hemostatic efficiency, it is degradable under in vivo conditions and supremely prevents bacterial growth. On the other hand, one of the drawbacks of the oxidized cellulose is cytotoxicity due to the strongly acidic nature during degradation. There is a number of commercially available oxidized cellulose products which are derived from regenerated and non-regenerated cellulose. On the other hand, the effect of oxidation degree and structure (regenerated or non-regenerated) on product efficiency is undetermined. Moreover, oxidation degree which is primary factor for both bactericidal and hemostatic efficiency is also crucial for assessment of the product. In this study, oxidized cellulose versus oxidized regenerated cellulose microparticles with various oxidation degree was produced and characterized. Comparative studies were conducted in terms of bactericidal and hemostatic efficiencies in addition to cytotoxicity. The results could be a reference for the optimized oxidized cellulose product for the hemostatic applications.</subfield>
  </datafield>
  <datafield tag="650" ind1="1" ind2="7">
    <subfield code="2">opendefinition.org</subfield>
    <subfield code="a">cc-by</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="u">TUBITAK Marmara Res Ctr, Inst Chem Technol, TR-41470 Kocaeli, Turkey</subfield>
    <subfield code="a">Sahin, Isa</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="u">Yeditepe Univ, Sch Med, Dept Immunol Sect, TR-34755 Istanbul, Turkey</subfield>
    <subfield code="a">Aru, Basak</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="u">TUBITAK Marmara Res Ctr, Mat Inst, TR-41470 Kocaeli, Turkey</subfield>
    <subfield code="a">Olmez, Hulya</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="u">Yeditepe Univ, Sch Med, Dept Immunol Sect, TR-34755 Istanbul, Turkey</subfield>
    <subfield code="a">Demirel, Gulderen Yanikkaya</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Sezer, Serdar</subfield>
  </datafield>
  <datafield tag="980" ind1=" " ind2=" ">
    <subfield code="b">article</subfield>
    <subfield code="a">publication</subfield>
  </datafield>
  <datafield tag="542" ind1=" " ind2=" ">
    <subfield code="l">open</subfield>
  </datafield>
  <datafield tag="100" ind1=" " ind2=" ">
    <subfield code="a">Sezer, Umran Aydemir</subfield>
  </datafield>
  <datafield tag="260" ind1=" " ind2=" ">
    <subfield code="c">2019-01-01</subfield>
  </datafield>
  <controlfield tag="005">20210316141840.0</controlfield>
  <datafield tag="909" ind1="C" ind2="O">
    <subfield code="o">oai:zenodo.org:99881</subfield>
    <subfield code="p">user-tubitak-adresli-yayinlar</subfield>
  </datafield>
  <datafield tag="856" ind1="4" ind2=" ">
    <subfield code="z">md5:90e147c1decbd772c0a21d6ba592bbd8</subfield>
    <subfield code="s">246</subfield>
    <subfield code="u">https://aperta.ulakbim.gov.trrecord/99881/files/bib-c2342a3f-4b71-4f1c-9e13-8263db992ced.txt</subfield>
  </datafield>
  <datafield tag="540" ind1=" " ind2=" ">
    <subfield code="u">http://www.opendefinition.org/licenses/cc-by</subfield>
    <subfield code="a">Creative Commons Attribution</subfield>
  </datafield>
  <datafield tag="024" ind1=" " ind2=" ">
    <subfield code="a">10.1016/j.carbpol.2019.05.005</subfield>
    <subfield code="2">doi</subfield>
  </datafield>
</record>