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Biophysical characterization of quaternary pyridinium functionalized polynorbornenes for DNA complexation and their cellular interactions

Gokce, Zeliha Guler; Birol, Semra Zuhal; Eren, Tarik; Ceylan, Sebnem Ercelen


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    <subfield code="a">Cationic polymers with hydrophobic side chains have gained great interest as DNA carriers since they form a compact complex with negatively charged DNA phosphate groups and interact with the cell membrane. Amphiphilic polyoxanorbornenes with different quaternary alkyl pyridinium side chains with ethyl- p(OPy2) and hexyl unitsp(OPy6) bearing 10 kDa MWT were synthesized by living Ring- Opening Metathesis Polymerization method.</subfield>
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