Dergi makalesi Açık Erişim

Biophysical characterization of quaternary pyridinium functionalized polynorbornenes for DNA complexation and their cellular interactions

2017    Gokce, Zeliha Guler; Birol, Semra Zuhal; Eren, Tarik; Ceylan, Sebnem Ercelen

Cationic polymers with hydrophobic side chains have gained great interest as DNA carriers since they form a compact complex with negatively charged DNA phosphate groups and interact with the cell membrane. Amphiphilic polyoxanorbornenes with different quaternary alkyl pyridinium side chains with ethyl- p(OPy2) and hexyl unitsp(OPy6) bearing 10 kDa MWT were synthesized by living Ring- Opening Metathesis Polymerization method.