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Biophysical characterization of quaternary pyridinium functionalized polynorbornenes for DNA complexation and their cellular interactions

Gokce, Zeliha Guler; Birol, Semra Zuhal; Eren, Tarik; Ceylan, Sebnem Ercelen


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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/90239</identifier>
  <creators>
    <creator>
      <creatorName>Gokce, Zeliha Guler</creatorName>
      <givenName>Zeliha Guler</givenName>
      <familyName>Gokce</familyName>
      <affiliation>TUBITAK Marmara Res Ctr, Genet Engn &amp; Biotechnol Inst, Gebze 21, TR-41470 Gebze, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Birol, Semra Zuhal</creatorName>
      <givenName>Semra Zuhal</givenName>
      <familyName>Birol</familyName>
      <affiliation>TUBITAK Marmara Res Ctr, Genet Engn &amp; Biotechnol Inst, Gebze 21, TR-41470 Gebze, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Eren, Tarik</creatorName>
      <givenName>Tarik</givenName>
      <familyName>Eren</familyName>
    </creator>
    <creator>
      <creatorName>Ceylan, Sebnem Ercelen</creatorName>
      <givenName>Sebnem Ercelen</givenName>
      <familyName>Ceylan</familyName>
      <affiliation>TUBITAK Marmara Res Ctr, Genet Engn &amp; Biotechnol Inst, Gebze 21, TR-41470 Gebze, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Biophysical Characterization Of Quaternary Pyridinium Functionalized Polynorbornenes For Dna Complexation And Their Cellular Interactions</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2017</publicationYear>
  <dates>
    <date dateType="Issued">2017-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/90239</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1002/bip.23005</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Cationic polymers with hydrophobic side chains have gained great interest as DNA carriers since they form a compact complex with negatively charged DNA phosphate groups and interact with the cell membrane. Amphiphilic polyoxanorbornenes with different quaternary alkyl pyridinium side chains with ethyl- p(OPy2) and hexyl unitsp(OPy6) bearing 10 kDa MWT were synthesized by living Ring- Opening Metathesis Polymerization method.</description>
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