1 Ocak 2020 Dergi makalesi Açık Erişim

Balcioglu, Bertan Koray; Oncu, Melis Denizci; Ozturk, Hasan Umit; Yucel, Fatima; Kaya, Filiz; Serhatli, Muge; Polat, Hivda Ulbegi; Tekin, Saban; Bahadir, Aylin Ozdemir

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{
  "@context": "https://schema.org/", 
  "@id": 89241, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "TUBITAK, Genet Engn & Biotechnol Inst, Marmara Res Ctr, Kocaeli, Turkey", 
      "name": "Balcioglu, Bertan Koray"
    }, 
    {
      "@type": "Person", 
      "affiliation": "TUBITAK, Genet Engn & Biotechnol Inst, Marmara Res Ctr, Kocaeli, Turkey", 
      "name": "Oncu, Melis Denizci"
    }, 
    {
      "@type": "Person", 
      "affiliation": "TUBITAK, Genet Engn & Biotechnol Inst, Marmara Res Ctr, Kocaeli, Turkey", 
      "name": "Ozturk, Hasan Umit"
    }, 
    {
      "@type": "Person", 
      "affiliation": "TUBITAK, Genet Engn & Biotechnol Inst, Marmara Res Ctr, Kocaeli, Turkey", 
      "name": "Yucel, Fatima"
    }, 
    {
      "@type": "Person", 
      "affiliation": "TUBITAK, Genet Engn & Biotechnol Inst, Marmara Res Ctr, Kocaeli, Turkey", 
      "name": "Kaya, Filiz"
    }, 
    {
      "@type": "Person", 
      "affiliation": "TUBITAK, Genet Engn & Biotechnol Inst, Marmara Res Ctr, Kocaeli, Turkey", 
      "name": "Serhatli, Muge"
    }, 
    {
      "@type": "Person", 
      "affiliation": "TUBITAK, Genet Engn & Biotechnol Inst, Marmara Res Ctr, Kocaeli, Turkey", 
      "name": "Polat, Hivda Ulbegi"
    }, 
    {
      "@type": "Person", 
      "name": "Tekin, Saban"
    }, 
    {
      "@type": "Person", 
      "affiliation": "TUBITAK, Genet Engn & Biotechnol Inst, Marmara Res Ctr, Kocaeli, Turkey", 
      "name": "Bahadir, Aylin Ozdemir"
    }
  ], 
  "datePublished": "2020-01-01", 
  "description": "In December 2019 a novel coronavirus was detected in Wuhan City of Hubei Province-China. Owing to a high rate of transmission from human to human, the new virus called SARS-CoV-2 differed from others by its unexpectedly rapid spread. The World Health Organization (WHO) described the most recent coronavirus epidemic as a global pandemic in March 2020. The virus spread triggered a health crisis (the COVID-19 disease) within three months, with socioeconomic implications. No approved targeted-therapies are available for COVID-19, yet. However, it is foreseen that antibody-based treatments may provide an immediate cure for patients. Current neutralizing antibody development studies primarily target the S protein among the structural elements of SARS-CoV-2, which mediates the cell entry of the virus through the angiotensin converting enzyme 2 (ACE2) receptor of host cells. This review aims to provide some of the neutralizing antibody development strategies for SARS-CoV-2 and in vitro and in vivo neutralization assays.", 
  "headline": "SARS-CoV-2 neutralizing antibody development strategies", 
  "identifier": 89241, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "SARS-CoV-2 neutralizing antibody development strategies", 
  "url": "https://aperta.ulakbim.gov.tr/record/89241"
}