1 Ocak 2020 Dergi makalesi Açık Erişim

Balcioglu, Bertan Koray; Oncu, Melis Denizci; Ozturk, Hasan Umit; Yucel, Fatima; Kaya, Filiz; Serhatli, Muge; Polat, Hivda Ulbegi; Tekin, Saban; Bahadir, Aylin Ozdemir

Dublin Core

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  <dc:creator>Balcioglu, Bertan Koray</dc:creator>
  <dc:creator>Oncu, Melis Denizci</dc:creator>
  <dc:creator>Ozturk, Hasan Umit</dc:creator>
  <dc:creator>Yucel, Fatima</dc:creator>
  <dc:creator>Kaya, Filiz</dc:creator>
  <dc:creator>Serhatli, Muge</dc:creator>
  <dc:creator>Polat, Hivda Ulbegi</dc:creator>
  <dc:creator>Tekin, Saban</dc:creator>
  <dc:creator>Bahadir, Aylin Ozdemir</dc:creator>
  <dc:date>2020-01-01</dc:date>
  <dc:description>In December 2019 a novel coronavirus was detected in Wuhan City of Hubei Province-China. Owing to a high rate of transmission from human to human, the new virus called SARS-CoV-2 differed from others by its unexpectedly rapid spread. The World Health Organization (WHO) described the most recent coronavirus epidemic as a global pandemic in March 2020. The virus spread triggered a health crisis (the COVID-19 disease) within three months, with socioeconomic implications. No approved targeted-therapies are available for COVID-19, yet. However, it is foreseen that antibody-based treatments may provide an immediate cure for patients. Current neutralizing antibody development studies primarily target the S protein among the structural elements of SARS-CoV-2, which mediates the cell entry of the virus through the angiotensin converting enzyme 2 (ACE2) receptor of host cells. This review aims to provide some of the neutralizing antibody development strategies for SARS-CoV-2 and in vitro and in vivo neutralization assays.</dc:description>
  <dc:identifier>https://aperta.ulakbim.gov.trrecord/89241</dc:identifier>
  <dc:identifier>oai:zenodo.org:89241</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://www.opendefinition.org/licenses/cc-by</dc:rights>
  <dc:source>TURKISH JOURNAL OF BIOLOGY 44(3) 203-214</dc:source>
  <dc:title>SARS-CoV-2 neutralizing antibody development strategies</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
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