1 Ocak 2020 Dergi makalesi Açık Erişim

Demir, Semsi Betul; Secinti, Hatice; Celebioglu, Neslihan; Ozdal, Murat; Sezen, Alev; Gulmez, Ozlem; Algur, Omer Faruk; Secen, Hasan

DataCite XML

<?xml version='1.0' encoding='utf-8'?>
<resource xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://datacite.org/schema/kernel-4" xsi:schemaLocation="http://datacite.org/schema/kernel-4 http://schema.datacite.org/meta/kernel-4.1/metadata.xsd">
  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/8221</identifier>
  <creators>
    <creator>
      <creatorName>Demir, Semsi Betul</creatorName>
      <givenName>Semsi Betul</givenName>
      <familyName>Demir</familyName>
      <affiliation>Ataturk Univ, Fac Sci, Dept Chem, Erzurum, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Secinti, Hatice</creatorName>
      <givenName>Hatice</givenName>
      <familyName>Secinti</familyName>
      <affiliation>Ataturk Univ, Fac Sci, Dept Chem, Erzurum, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Celebioglu, Neslihan</creatorName>
      <givenName>Neslihan</givenName>
      <familyName>Celebioglu</familyName>
      <affiliation>Ataturk Univ, Fac Sci, Dept Chem, Erzurum, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Ozdal, Murat</creatorName>
      <givenName>Murat</givenName>
      <familyName>Ozdal</familyName>
      <affiliation>Ataturk Univ, Fac Sci, Dept Biol, Erzurum, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Sezen, Alev</creatorName>
      <givenName>Alev</givenName>
      <familyName>Sezen</familyName>
      <affiliation>Ataturk Univ, Fac Sci, Dept Biol, Erzurum, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Gulmez, Ozlem</creatorName>
      <givenName>Ozlem</givenName>
      <familyName>Gulmez</familyName>
      <affiliation>Ataturk Univ, Fac Sci, Dept Biol, Erzurum, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Algur, Omer Faruk</creatorName>
      <givenName>Omer Faruk</givenName>
      <familyName>Algur</familyName>
      <affiliation>Ataturk Univ, Fac Sci, Dept Biol, Erzurum, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Secen, Hasan</creatorName>
      <givenName>Hasan</givenName>
      <familyName>Secen</familyName>
      <affiliation>Ataturk Univ, Fac Sci, Dept Chem, Erzurum, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Syntheses And Antibacterial Activities Of 4 Linear Nonphenolic Diarylheptanoids</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2020</publicationYear>
  <dates>
    <date dateType="Issued">2020-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/8221</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.3906/kim-1911-61</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Four linear nonphenolic diarylheptanoids were synthesized and their antibacterial activities were studied. (S)-2-Me-CBS-catalysed reduction of alnustone with BH3.SMe2 gave (R) (-)(4E,6E)-1,7-diphenylhepta-4,6-dien-3-ol, a natural product. Reduction of alnustone with Na in t-BuOH at -15 degrees C under NH3 atm gave ( E)-1,7-diphenylhept-5-en-3-one as a Birch-type reduction product. t-BuOK catalysed condensation of benzalacetone with propionyl chloride gave (4Z,6E)-5-hydroxy-1,7-diphenylhepta-4,6-dien-3-one, a natural product. (1E,4Z,6E)-5-Hydroxy-4-phenethyl-1,7-diphenylhepta-1,4,6-trien-3-one, a curcuminoid, was synthesized starting from pentan-2,4-dione in 3 steps. The synthesized chemical compounds were applied against 2 gram-positive bacteria (Bacillus cereus and Arthrobacter agilis), 4 gram-negative bacteria (Pseudomonas aeruginosa, Xanthomonas campestris, Klebsiella oxytoca, and Helicobacter pylori), and 1 yeast (Candida albicans) by the disc diffusion method. All of the synthesized compound exhibited different degrees of antimicrobial activity at concentrations between 20-100 mu g/disc against the test organisms.</description>
  </descriptions>
</resource>