Dergi makalesi Açık Erişim
Bingol, H. Betul; Altin, Ayse; Bal, Tugba; Agopcan-Cinar, Sesil; Kizilel, Seda; Avci, Duygu
<?xml version='1.0' encoding='UTF-8'?> <record xmlns="http://www.loc.gov/MARC21/slim"> <leader>00000nam##2200000uu#4500</leader> <datafield tag="245" ind1=" " ind2=" "> <subfield code="a">Synthesis and evaluation of new phosphonic acid-functionalized acrylamides with potential biomedical applications</subfield> </datafield> <datafield tag="909" ind1="C" ind2="4"> <subfield code="p">JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY</subfield> <subfield code="v">53</subfield> <subfield code="n">23</subfield> <subfield code="c">2755-2767</subfield> </datafield> <controlfield tag="001">78891</controlfield> <datafield tag="980" ind1=" " ind2=" "> <subfield code="a">user-tubitak-destekli-proje-yayinlari</subfield> </datafield> <datafield tag="520" ind1=" " ind2=" "> <subfield code="a">Phosphorus-containing acidic monomers are able to interact with the inorganic phase of mineralized tissues such as enamel, dentin, and bone. From this perspective, three phosphonic acid-containing acrylamide monomers with different lengths of alkyl chains were synthesized to be used for both self-etching dental adhesives and mineralized hydrogel scaffolds. Monomers were synthesized by the reaction of -aminophosphonates (diethyl aminomethylphosphonate, diethyl 2-aminobutan-2-ylphosphonate, and diethyl 2-aminooctan-2-ylphosphonate) with acryloyl chloride followed by the hydrolysis of phosphonate groups by using trimethylsilyl bromide. The properties such as pH in the range of mild self-etching adhesives, hydrolytic stability, high rate of copolymerizations with 2-hydroxyethyl methacrylate (HEMA) and HEMA/glycerol dimethacrylate, giving high-molecular-weight polymers on thermal polymerization, and strong decalcification ability of hydroxyapatite make these monomers good candidates for self-etching adhesives, although no appreciable effect of the number and size of the -substituents was observed. Hydrogel scaffolds containing phosphonic acid groups were fabricated, characterized, and mineralized. Altogether, the results suggest that these phosphonic acid-containing monomers have suitable properties to be used in fabrication of biomaterials for both dental and bone tissue engineering applications. (c) 2015 Wiley Periodicals, Inc.</subfield> </datafield> <datafield tag="650" ind1="1" ind2="7"> <subfield code="2">opendefinition.org</subfield> <subfield code="a">cc-by</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Bogazici Univ, Dept Chem, TR-34342 Istanbul, Turkey</subfield> <subfield code="a">Altin, Ayse</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Koc Univ, Dept Chem & Biol Engn, TR-34450 Istanbul, Turkey</subfield> <subfield code="a">Bal, Tugba</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Bogazici Univ, Dept Chem, TR-34342 Istanbul, Turkey</subfield> <subfield code="a">Agopcan-Cinar, Sesil</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Koc Univ, Dept Chem & Biol Engn, TR-34450 Istanbul, Turkey</subfield> <subfield code="a">Kizilel, Seda</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Bogazici Univ, Dept Chem, TR-34342 Istanbul, Turkey</subfield> <subfield code="a">Avci, Duygu</subfield> </datafield> <datafield tag="980" ind1=" " ind2=" "> <subfield code="b">article</subfield> <subfield code="a">publication</subfield> </datafield> <datafield tag="542" ind1=" " ind2=" "> <subfield code="l">open</subfield> </datafield> <datafield tag="100" ind1=" " ind2=" "> <subfield code="u">Bogazici Univ, Dept Chem, TR-34342 Istanbul, Turkey</subfield> <subfield code="a">Bingol, H. Betul</subfield> </datafield> <datafield tag="260" ind1=" " ind2=" "> <subfield code="c">2015-01-01</subfield> </datafield> <controlfield tag="005">20210316051258.0</controlfield> <datafield tag="909" ind1="C" ind2="O"> <subfield code="o">oai:zenodo.org:78891</subfield> <subfield code="p">user-tubitak-destekli-proje-yayinlari</subfield> </datafield> <datafield tag="856" ind1="4" ind2=" "> <subfield code="z">md5:220b8bbcbaac66610db1d7651b99f834</subfield> <subfield code="s">268</subfield> <subfield code="u">https://aperta.ulakbim.gov.trrecord/78891/files/bib-8b3a80d9-8328-4eb2-8e82-e264a16123df.txt</subfield> </datafield> <datafield tag="540" ind1=" " ind2=" "> <subfield code="u">http://www.opendefinition.org/licenses/cc-by</subfield> <subfield code="a">Creative Commons Attribution</subfield> </datafield> <datafield tag="024" ind1=" " ind2=" "> <subfield code="a">10.1002/pola.27746</subfield> <subfield code="2">doi</subfield> </datafield> </record>
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