1 Ocak 2015 Dergi makalesi Açık Erişim

Bingol, H. Betul; Altin, Ayse; Bal, Tugba; Agopcan-Cinar, Sesil; Kizilel, Seda; Avci, Duygu

JSON

{
  "conceptrecid": "78890", 
  "created": "2021-03-16T05:12:58.476425+00:00", 
  "doi": "10.1002/pola.27746", 
  "files": [
    {
      "bucket": "bda94c1b-2975-4b35-b019-bc22c24a2f88", 
      "checksum": "md5:220b8bbcbaac66610db1d7651b99f834", 
      "key": "bib-8b3a80d9-8328-4eb2-8e82-e264a16123df.txt", 
      "links": {
        "self": "https://aperta.ulakbim.gov.tr/api/files/bda94c1b-2975-4b35-b019-bc22c24a2f88/bib-8b3a80d9-8328-4eb2-8e82-e264a16123df.txt"
      }, 
      "size": 268, 
      "type": "txt"
    }
  ], 
  "id": 78891, 
  "links": {
    "badge": "https://aperta.ulakbim.gov.tr/badge/doi/10.1002/pola.27746.svg", 
    "bucket": "https://aperta.ulakbim.gov.tr/api/files/bda94c1b-2975-4b35-b019-bc22c24a2f88", 
    "doi": "https://doi.org/10.1002/pola.27746", 
    "html": "https://aperta.ulakbim.gov.tr/record/78891", 
    "latest": "https://aperta.ulakbim.gov.tr/api/records/78891", 
    "latest_html": "https://aperta.ulakbim.gov.tr/record/78891"
  }, 
  "metadata": {
    "access_right": "open", 
    "access_right_category": "success", 
    "communities": [
      {
        "id": "tubitak-destekli-proje-yayinlari"
      }
    ], 
    "creators": [
      {
        "affiliation": "Bogazici Univ, Dept Chem, TR-34342 Istanbul, Turkey", 
        "name": "Bingol, H. Betul"
      }, 
      {
        "affiliation": "Bogazici Univ, Dept Chem, TR-34342 Istanbul, Turkey", 
        "name": "Altin, Ayse"
      }, 
      {
        "affiliation": "Koc Univ, Dept Chem & Biol Engn, TR-34450 Istanbul, Turkey", 
        "name": "Bal, Tugba"
      }, 
      {
        "affiliation": "Bogazici Univ, Dept Chem, TR-34342 Istanbul, Turkey", 
        "name": "Agopcan-Cinar, Sesil"
      }, 
      {
        "affiliation": "Koc Univ, Dept Chem & Biol Engn, TR-34450 Istanbul, Turkey", 
        "name": "Kizilel, Seda"
      }, 
      {
        "affiliation": "Bogazici Univ, Dept Chem, TR-34342 Istanbul, Turkey", 
        "name": "Avci, Duygu"
      }
    ], 
    "description": "Phosphorus-containing acidic monomers are able to interact with the inorganic phase of mineralized tissues such as enamel, dentin, and bone. From this perspective, three phosphonic acid-containing acrylamide monomers with different lengths of alkyl chains were synthesized to be used for both self-etching dental adhesives and mineralized hydrogel scaffolds. Monomers were synthesized by the reaction of -aminophosphonates (diethyl aminomethylphosphonate, diethyl 2-aminobutan-2-ylphosphonate, and diethyl 2-aminooctan-2-ylphosphonate) with acryloyl chloride followed by the hydrolysis of phosphonate groups by using trimethylsilyl bromide. The properties such as pH in the range of mild self-etching adhesives, hydrolytic stability, high rate of copolymerizations with 2-hydroxyethyl methacrylate (HEMA) and HEMA/glycerol dimethacrylate, giving high-molecular-weight polymers on thermal polymerization, and strong decalcification ability of hydroxyapatite make these monomers good candidates for self-etching adhesives, although no appreciable effect of the number and size of the -substituents was observed. Hydrogel scaffolds containing phosphonic acid groups were fabricated, characterized, and mineralized. Altogether, the results suggest that these phosphonic acid-containing monomers have suitable properties to be used in fabrication of biomaterials for both dental and bone tissue engineering applications. (c) 2015 Wiley Periodicals, Inc.", 
    "doi": "10.1002/pola.27746", 
    "has_grant": false, 
    "journal": {
      "issue": "23", 
      "pages": "2755-2767", 
      "title": "JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY", 
      "volume": "53"
    }, 
    "license": {
      "id": "cc-by"
    }, 
    "publication_date": "2015-01-01", 
    "relations": {
      "version": [
        {
          "count": 1, 
          "index": 0, 
          "is_last": true, 
          "last_child": {
            "pid_type": "recid", 
            "pid_value": "78891"
          }, 
          "parent": {
            "pid_type": "recid", 
            "pid_value": "78890"
          }
        }
      ]
    }, 
    "resource_type": {
      "subtype": "article", 
      "title": "Dergi makalesi", 
      "type": "publication"
    }, 
    "title": "Synthesis and evaluation of new phosphonic acid-functionalized acrylamides with potential biomedical applications"
  }, 
  "owners": [
    1
  ], 
  "revision": 1, 
  "stats": {
    "downloads": 4.0, 
    "unique_downloads": 4.0, 
    "unique_views": 38.0, 
    "version_downloads": 4.0, 
    "version_unique_downloads": 4.0, 
    "version_unique_views": 38.0, 
    "version_views": 41.0, 
    "version_volume": 1072.0, 
    "views": 41.0, 
    "volume": 1072.0
  }, 
  "updated": "2021-03-16T05:12:58.534779+00:00"
}