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Ekineker, Guelcin; Nguyen, Christophe; Bayir, Suemeyra; Dominguez Gil, Sofia; Isci, Umit; Daurat, Morgane; Godefroy, Anastasia; Raehm, Laurence; Charnay, Clarence; Oliviero, Erwan; Ahsen, Vefa; Gary-Bobo, Magali; Durand, Jean-Olivier; Dumoulin, Fabienne
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{
"@type": "Person",
"affiliation": "Gebze Tech Univ, Dept Chem, TR-41400 Gebze, Turkey",
"name": "Ekineker, Guelcin"
},
{
"@type": "Person",
"affiliation": "Univ Montpellier, Inst Biomol Max Mousseron, UMR 5247, 15 Ave Charles Flahault, F-34093 Montpellier 05, France",
"name": "Nguyen, Christophe"
},
{
"@type": "Person",
"affiliation": "Gebze Tech Univ, Dept Chem, TR-41400 Gebze, Turkey",
"name": "Bayir, Suemeyra"
},
{
"@type": "Person",
"affiliation": "CNRS, Inst Charles Gerhardt Montpellier, UMR 5253, UM,ENSCM, Cc 1701,Pl Eugene Bataillon, F-34095 Montpellier 05, France",
"name": "Dominguez Gil, Sofia"
},
{
"@type": "Person",
"affiliation": "Gebze Tech Univ, Dept Chem, TR-41400 Gebze, Turkey",
"name": "Isci, Umit"
},
{
"@type": "Person",
"affiliation": "Univ Montpellier, Inst Biomol Max Mousseron, UMR 5247, 15 Ave Charles Flahault, F-34093 Montpellier 05, France",
"name": "Daurat, Morgane"
},
{
"@type": "Person",
"name": "Godefroy, Anastasia"
},
{
"@type": "Person",
"affiliation": "CNRS, Inst Charles Gerhardt Montpellier, UMR 5253, UM,ENSCM, Cc 1701,Pl Eugene Bataillon, F-34095 Montpellier 05, France",
"name": "Raehm, Laurence"
},
{
"@type": "Person",
"affiliation": "CNRS, Inst Charles Gerhardt Montpellier, UMR 5253, UM,ENSCM, Cc 1701,Pl Eugene Bataillon, F-34095 Montpellier 05, France",
"name": "Charnay, Clarence"
},
{
"@type": "Person",
"affiliation": "CNRS, Inst Charles Gerhardt Montpellier, UMR 5253, UM,ENSCM, Cc 1701,Pl Eugene Bataillon, F-34095 Montpellier 05, France",
"name": "Oliviero, Erwan"
},
{
"@type": "Person",
"affiliation": "Gebze Tech Univ, Dept Chem, TR-41400 Gebze, Turkey",
"name": "Ahsen, Vefa"
},
{
"@type": "Person",
"affiliation": "Univ Montpellier, Inst Biomol Max Mousseron, UMR 5247, 15 Ave Charles Flahault, F-34093 Montpellier 05, France",
"name": "Gary-Bobo, Magali"
},
{
"@type": "Person",
"affiliation": "CNRS, Inst Charles Gerhardt Montpellier, UMR 5253, UM,ENSCM, Cc 1701,Pl Eugene Bataillon, F-34095 Montpellier 05, France",
"name": "Durand, Jean-Olivier"
},
{
"@type": "Person",
"affiliation": "Gebze Tech Univ, Dept Chem, TR-41400 Gebze, Turkey",
"name": "Dumoulin, Fabienne"
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],
"datePublished": "2019-01-01",
"description": "Mesoporous organosilica nanoparticles (PHT-PMO) have been prepared from an octa-triethoxysilylated Zn phthalocyanine precursor. These PHT-PMO nanoparticles had no dark toxicity but high phototoxicity when irradiated at 650 nm, and remarkable near-infrared phototoxicity when excited at 760 and 810 nm. The PHT-PMO were then aminated to promote electrostatic complexation with siRNA. Transfection experiments were performed upon NIR irradiation and photochemical internalization was very efficient, leading to 65% luciferase extinction in MCF-7 cancer cells expressing stable luciferase.",
"headline": "Phthalocyanine-based mesoporous organosilica nanoparticles: NIR photodynamic efficiency and siRNA photochemical internalization",
"identifier": 67455,
"image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg",
"license": "http://www.opendefinition.org/licenses/cc-by",
"name": "Phthalocyanine-based mesoporous organosilica nanoparticles: NIR photodynamic efficiency and siRNA photochemical internalization",
"url": "https://aperta.ulakbim.gov.tr/record/67455"
}
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