1 Ocak 2019 Dergi makalesi Açık Erişim

Ekineker, Guelcin; Nguyen, Christophe; Bayir, Suemeyra; Dominguez Gil, Sofia; Isci, Umit; Daurat, Morgane; Godefroy, Anastasia; Raehm, Laurence; Charnay, Clarence; Oliviero, Erwan; Ahsen, Vefa; Gary-Bobo, Magali; Durand, Jean-Olivier; Dumoulin, Fabienne

Citation Style Language JSON

{
  "DOI": "10.1039/c9cc05703j", 
  "abstract": "Mesoporous organosilica nanoparticles (PHT-PMO) have been prepared from an octa-triethoxysilylated Zn phthalocyanine precursor. These PHT-PMO nanoparticles had no dark toxicity but high phototoxicity when irradiated at 650 nm, and remarkable near-infrared phototoxicity when excited at 760 and 810 nm. The PHT-PMO were then aminated to promote electrostatic complexation with siRNA. Transfection experiments were performed upon NIR irradiation and photochemical internalization was very efficient, leading to 65% luciferase extinction in MCF-7 cancer cells expressing stable luciferase.", 
  "author": [
    {
      "family": "Ekineker", 
      "given": " Guelcin"
    }, 
    {
      "family": "Nguyen", 
      "given": " Christophe"
    }, 
    {
      "family": "Bayir", 
      "given": " Suemeyra"
    }, 
    {
      "family": "Dominguez Gil", 
      "given": " Sofia"
    }, 
    {
      "family": "Isci", 
      "given": " Umit"
    }, 
    {
      "family": "Daurat", 
      "given": " Morgane"
    }, 
    {
      "family": "Godefroy", 
      "given": " Anastasia"
    }, 
    {
      "family": "Raehm", 
      "given": " Laurence"
    }, 
    {
      "family": "Charnay", 
      "given": " Clarence"
    }, 
    {
      "family": "Oliviero", 
      "given": " Erwan"
    }, 
    {
      "family": "Ahsen", 
      "given": " Vefa"
    }, 
    {
      "family": "Gary-Bobo", 
      "given": " Magali"
    }, 
    {
      "family": "Durand", 
      "given": " Jean-Olivier"
    }, 
    {
      "family": "Dumoulin", 
      "given": " Fabienne"
    }
  ], 
  "container_title": "CHEMICAL COMMUNICATIONS", 
  "id": "67455", 
  "issue": "77", 
  "issued": {
    "date-parts": [
      [
        2019, 
        1, 
        1
      ]
    ]
  }, 
  "page": "11619-11622", 
  "title": "Phthalocyanine-based mesoporous organosilica nanoparticles: NIR photodynamic efficiency and siRNA photochemical internalization", 
  "type": "article-journal", 
  "volume": "55"
}