1 Ocak 2016 Dergi makalesi Açık Erişim

Topkaya, Derya; Lafont, Dominique; Poyer, Florent; Garcia, Guillaume; Albrieux, Florian; Maillard, Philippe; Bretonniere, Yann; Dumoulin, Fabienne

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    <subfield code="a">Design of an amphiphilic porphyrin exhibiting high in vitro photocytotoxicity</subfield>
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    <subfield code="a">A porphyrin monosubstituted by three triethyleneglycol chains grafted on a pentaerythritol skeleton was designed to display an optimized amphiphilicity for an enhanced cellular uptake and thus to exert enhanced photocytotoxicity. This porphyrin proved to be an excellent photosensitiser with submicromolar IC50.</subfield>
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