1 Ocak 2016 Dergi makalesi Açık Erişim

Acharya, Chayan; Hookers, Andrew C.; Turkyilmaz, Gulbeyaz Yildiz; Jonsson, Siu; Karlsson, Mats O.

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    <subfield code="a">Background and objective: Non-compartmental analysis (NCA) calculates pharmacokinetic (PK) metrics related to the systemic exposure to a drug following administration, e.g. area under the concentration time curve and peak concentration. We developed a new package in R, called ncappc, to perform (i) a NCA and (ii) simulation-based posterior predictive checks (ppc) for a population PK (PopPK) model using NCA metrics.</subfield>
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    <subfield code="a">A diagnostic tool for population models using non-compartmental analysis: The ncappc package for R</subfield>
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