1 Ocak 2016 Dergi makalesi Açık Erişim

Acharya, Chayan; Hookers, Andrew C.; Turkyilmaz, Gulbeyaz Yildiz; Jonsson, Siu; Karlsson, Mats O.

DataCite XML

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/54201</identifier>
  <creators>
    <creator>
      <creatorName>Acharya, Chayan</creatorName>
      <givenName>Chayan</givenName>
      <familyName>Acharya</familyName>
      <affiliation>Uppsala Univ, Dept Pharmaceut Biosci, POB 591, SE-75124 Uppsala, Sweden</affiliation>
    </creator>
    <creator>
      <creatorName>Hookers, Andrew C.</creatorName>
      <givenName>Andrew C.</givenName>
      <familyName>Hookers</familyName>
      <affiliation>Uppsala Univ, Dept Pharmaceut Biosci, POB 591, SE-75124 Uppsala, Sweden</affiliation>
    </creator>
    <creator>
      <creatorName>Turkyilmaz, Gulbeyaz Yildiz</creatorName>
      <givenName>Gulbeyaz Yildiz</givenName>
      <familyName>Turkyilmaz</familyName>
    </creator>
    <creator>
      <creatorName>Jonsson, Siu</creatorName>
      <givenName>Siu</givenName>
      <familyName>Jonsson</familyName>
      <affiliation>Uppsala Univ, Dept Pharmaceut Biosci, POB 591, SE-75124 Uppsala, Sweden</affiliation>
    </creator>
    <creator>
      <creatorName>Karlsson, Mats O.</creatorName>
      <givenName>Mats O.</givenName>
      <familyName>Karlsson</familyName>
      <affiliation>Uppsala Univ, Dept Pharmaceut Biosci, POB 591, SE-75124 Uppsala, Sweden</affiliation>
    </creator>
  </creators>
  <titles>
    <title>A Diagnostic Tool For Population Models Using Non-Compartmental Analysis: The Ncappc Package For R</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2016</publicationYear>
  <dates>
    <date dateType="Issued">2016-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/54201</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1016/j.cmpb.2016.01.013</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Background and objective: Non-compartmental analysis (NCA) calculates pharmacokinetic (PK) metrics related to the systemic exposure to a drug following administration, e.g. area under the concentration time curve and peak concentration. We developed a new package in R, called ncappc, to perform (i) a NCA and (ii) simulation-based posterior predictive checks (ppc) for a population PK (PopPK) model using NCA metrics.</description>
  </descriptions>
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