1 Ocak 2016 Dergi makalesi Açık Erişim

Acharya, Chayan; Hookers, Andrew C.; Turkyilmaz, Gulbeyaz Yildiz; Jonsson, Siu; Karlsson, Mats O.

Citation Style Language JSON

{
  "DOI": "10.1016/j.cmpb.2016.01.013", 
  "abstract": "Background and objective: Non-compartmental analysis (NCA) calculates pharmacokinetic (PK) metrics related to the systemic exposure to a drug following administration, e.g. area under the concentration time curve and peak concentration. We developed a new package in R, called ncappc, to perform (i) a NCA and (ii) simulation-based posterior predictive checks (ppc) for a population PK (PopPK) model using NCA metrics.", 
  "author": [
    {
      "family": "Acharya", 
      "given": " Chayan"
    }, 
    {
      "family": "Hookers", 
      "given": " Andrew C."
    }, 
    {
      "family": "Turkyilmaz", 
      "given": " Gulbeyaz Yildiz"
    }, 
    {
      "family": "Jonsson", 
      "given": " Siu"
    }, 
    {
      "family": "Karlsson", 
      "given": " Mats O."
    }
  ], 
  "container_title": "COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE", 
  "id": "54201", 
  "issued": {
    "date-parts": [
      [
        2016, 
        1, 
        1
      ]
    ]
  }, 
  "page": "83-93", 
  "title": "A diagnostic tool for population models using non-compartmental analysis: The ncappc package for R", 
  "type": "article-journal", 
  "volume": "127"
}