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Genome sequence analysis of a Helicoverpa armigera single nucleopolyhedrovirus (HearNPV-TR) isolated fromHeliothis peltigera in Turkey

Eroglu, Gozde Busra; Inan, Cihan; Nalcacioglu, Remziye; Demirbag, Zihni


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{
  "DOI": "10.1371/journal.pone.0234635", 
  "abstract": "The entire genome of Helicoverpa armigera single nucleopolyhedrovirus (HearNPV-TR) was sequenced, and compared to genomes of other existing isolates. HearNPV-TR genome is 130.691 base pairs with a 38.9% G+C content and has 137 open reading frames (ORFs) of >= 150 nucleotides. Five homologous repeated sequences (hrs) and two baculovirus repeated ORFs (bro-a andbro-b) were identified. Phylogenetic analysis showed that HearNPV-TR is closer to HaSNPV-C1, HaSNPV-G4, HaSNPV-AU and HasNPV. However, there are significant differences inhr3,hr5 regions and inbro-a gene. Pairwise Kimura-2 parameter analysis of 38 core genes sequences of HearNPV-TR and other Helicoverpa NPVs showed that the genetic distances for these sequences were below 0.015 substitutions/site. Genomic differences as revealed by restriction profiles indicated thathr3,hr5regions andbro-a gene may play a role in the virulence of HearNPV-TR.", 
  "author": [
    {
      "family": "Eroglu", 
      "given": " Gozde Busra"
    }, 
    {
      "family": "Inan", 
      "given": " Cihan"
    }, 
    {
      "family": "Nalcacioglu", 
      "given": " Remziye"
    }, 
    {
      "family": "Demirbag", 
      "given": " Zihni"
    }
  ], 
  "container_title": "PLOS ONE", 
  "id": "5269", 
  "issue": "6", 
  "issued": {
    "date-parts": [
      [
        2020, 
        1, 
        1
      ]
    ]
  }, 
  "title": "Genome sequence analysis of a Helicoverpa armigera single nucleopolyhedrovirus (HearNPV-TR) isolated fromHeliothis peltigera in Turkey", 
  "type": "article-journal", 
  "volume": "15"
}
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