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Deficiency of Complement 1r Subcomponent in Early-Onset Systemic Lupus Erythematosus: The Role of Disease-Modifying Alleles in a Monogenic Disease

Demirkaya, Erkan; Zhou, Qing; Smith, Carolyne K.; Ombrello, Michael J.; Deuitch, Natalie; Tsai, Wanxia L.; Hoffmann, Patrycja; Remmers, Elaine F.; Takeuchi, Masaki; Park, Yong Hwan; Chae, JaeJin; Barut, Kenan; Simsek, Dogan; Adrovic, Amra; Sahin, Sezgin; Caliskan, Salim; Chandrasekharappa, Settara C.; Hasni, Sarfaraz A.; Ombrello, Amanda K.; Gadina, Massimo; Gadina, Massimo


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      "affiliation": "NIAMSD, NIH, Bethesda, MD 20892 USA", 
      "name": "Tsai, Wanxia L."
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      "name": "Hoffmann, Patrycja"
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      "name": "Park, Yong Hwan"
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      "@type": "Person", 
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      "name": "Chae, JaeJin"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Istanbul Univ, Istanbul, Turkey", 
      "name": "Barut, Kenan"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Gulhane Educ & Res Hosp, Ankara, Turkey", 
      "name": "Simsek, Dogan"
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    {
      "@type": "Person", 
      "affiliation": "Istanbul Univ, Istanbul, Turkey", 
      "name": "Adrovic, Amra"
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      "@type": "Person", 
      "affiliation": "Istanbul Univ, Istanbul, Turkey", 
      "name": "Sahin, Sezgin"
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      "affiliation": "Istanbul Univ, Istanbul, Turkey", 
      "name": "Caliskan, Salim"
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      "affiliation": "NHGRI, NIH, CRC Bldg 10,Room B2-5235,9000 Rockville Pike, Bethesda, MD 20892 USA", 
      "name": "Chandrasekharappa, Settara C."
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      "@type": "Person", 
      "affiliation": "NIAMSD, NIH, Bethesda, MD 20892 USA", 
      "name": "Hasni, Sarfaraz A."
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      "name": "Gadina, Massimo"
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  ], 
  "datePublished": "2017-01-01", 
  "description": "Objective. To identify a genetic cause of early-onset systemic lupus erythematosus (SLE) in a large consanguineous family from Turkey and to study the mechanisms of the disease.", 
  "headline": "Deficiency of Complement 1r Subcomponent in Early-Onset Systemic Lupus Erythematosus: The Role of Disease-Modifying Alleles in a Monogenic Disease", 
  "identifier": 45703, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Deficiency of Complement 1r Subcomponent in Early-Onset Systemic Lupus Erythematosus: The Role of Disease-Modifying Alleles in a Monogenic Disease", 
  "url": "https://aperta.ulakbim.gov.tr/record/45703"
}
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