Dergi makalesi Açık Erişim

Deficiency of Complement 1r Subcomponent in Early-Onset Systemic Lupus Erythematosus: The Role of Disease-Modifying Alleles in a Monogenic Disease

2017    Demirkaya, Erkan; Zhou, Qing; Smith, Carolyne K.; Ombrello, Michael J.; Deuitch, Natalie; Tsai, Wanxia L.; Hoffmann, Patrycja; Remmers, Elaine F.; Takeuchi, Masaki; Park, Yong Hwan; Chae, JaeJin; Barut, Kenan; Simsek, Dogan; Adrovic, Amra; Sahin, Sezgin; Caliskan, Salim; Chandrasekharappa, Settara C.; Hasni, Sarfaraz A.; Ombrello, Amanda K.; Gadina, Massimo; Gadina, Massimo

Objective. To identify a genetic cause of early-onset systemic lupus erythematosus (SLE) in a large consanguineous family from Turkey and to study the mechanisms of the disease.