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Deficiency of Complement 1r Subcomponent in Early-Onset Systemic Lupus Erythematosus: The Role of Disease-Modifying Alleles in a Monogenic Disease

Demirkaya, Erkan; Zhou, Qing; Smith, Carolyne K.; Ombrello, Michael J.; Deuitch, Natalie; Tsai, Wanxia L.; Hoffmann, Patrycja; Remmers, Elaine F.; Takeuchi, Masaki; Park, Yong Hwan; Chae, JaeJin; Barut, Kenan; Simsek, Dogan; Adrovic, Amra; Sahin, Sezgin; Caliskan, Salim; Chandrasekharappa, Settara C.; Hasni, Sarfaraz A.; Ombrello, Amanda K.; Gadina, Massimo; Gadina, Massimo


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{
  "DOI": "10.1002/art.40158", 
  "abstract": "Objective. To identify a genetic cause of early-onset systemic lupus erythematosus (SLE) in a large consanguineous family from Turkey and to study the mechanisms of the disease.", 
  "author": [
    {
      "family": "Demirkaya", 
      "given": " Erkan"
    }, 
    {
      "family": "Zhou", 
      "given": " Qing"
    }, 
    {
      "family": "Smith", 
      "given": " Carolyne K."
    }, 
    {
      "family": "Ombrello", 
      "given": " Michael J."
    }, 
    {
      "family": "Deuitch", 
      "given": " Natalie"
    }, 
    {
      "family": "Tsai", 
      "given": " Wanxia L."
    }, 
    {
      "family": "Hoffmann", 
      "given": " Patrycja"
    }, 
    {
      "family": "Remmers", 
      "given": " Elaine F."
    }, 
    {
      "family": "Takeuchi", 
      "given": " Masaki"
    }, 
    {
      "family": "Park", 
      "given": " Yong Hwan"
    }, 
    {
      "family": "Chae", 
      "given": " JaeJin"
    }, 
    {
      "family": "Barut", 
      "given": " Kenan"
    }, 
    {
      "family": "Simsek", 
      "given": " Dogan"
    }, 
    {
      "family": "Adrovic", 
      "given": " Amra"
    }, 
    {
      "family": "Sahin", 
      "given": " Sezgin"
    }, 
    {
      "family": "Caliskan", 
      "given": " Salim"
    }, 
    {
      "family": "Chandrasekharappa", 
      "given": " Settara C."
    }, 
    {
      "family": "Hasni", 
      "given": " Sarfaraz A."
    }, 
    {
      "family": "Ombrello", 
      "given": " Amanda K."
    }, 
    {
      "family": "Gadina", 
      "given": " Massimo"
    }, 
    {
      "family": "Gadina", 
      "given": " Massimo"
    }
  ], 
  "container_title": "ARTHRITIS & RHEUMATOLOGY", 
  "id": "45703", 
  "issue": "9", 
  "issued": {
    "date-parts": [
      [
        2017, 
        1, 
        1
      ]
    ]
  }, 
  "page": "1832-1839", 
  "title": "Deficiency of Complement 1r Subcomponent in Early-Onset Systemic Lupus Erythematosus: The Role of Disease-Modifying Alleles in a Monogenic Disease", 
  "type": "article-journal", 
  "volume": "69"
}
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