Dergi makalesi Açık Erişim
Gorgulu, G.; Cicek, M. B.; Dede, B.
{
"@context": "https://schema.org/",
"@id": 32521,
"@type": "ScholarlyArticle",
"creator": [
{
"@type": "Person",
"affiliation": "Mehmet Akif Ersoy Univ, Fac Educ, Burdur, Turkey",
"name": "Gorgulu, G."
},
{
"@type": "Person",
"affiliation": "Suleyman Demirel Univ, Fac Sci & Arts, Isparta, Turkey",
"name": "Cicek, M. B."
},
{
"@type": "Person",
"affiliation": "Suleyman Demirel Univ, Fac Sci & Arts, Isparta, Turkey",
"name": "Dede, B."
}
],
"datePublished": "2018-01-01",
"description": "A novel ligand, N, N ''-(4-methyl-1,2-phenylene)bis(2-(biphenyl-4-yl)-N'-hydroxy-2-oxoacetimidamide) (H2L) with its Cu(II) and Mn(II) complexes were synthesized in this study. All compounds synthesized were also characterized by H-1- and C-13-NMR, the Fourier transform infrared, elemental analysis, inductively coupled plasma optical emission spectrometry, molar conductivity, magnetic susceptibility measurements and thermogravimetric analysis. Vascular endothelial growth factor-2 (VEGFR-2) and cyclooxygenase-2 (COX-2) inhibition is often used as a parameter for being a potent anticancer agent in docking studies. For this purpose, synthesized and characterized ligand was investigated by molecular docking study to test its inhibitory effect against angiogenic factors VEGFR-2 and COX-2.",
"headline": "Novel Aminoketooxime Ligand and Its Cu(II) and Mn(II) Complexes: Synthesis, Characterization and Molecular Docking Studies",
"identifier": 32521,
"image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg",
"license": "http://www.opendefinition.org/licenses/cc-by",
"name": "Novel Aminoketooxime Ligand and Its Cu(II) and Mn(II) Complexes: Synthesis, Characterization and Molecular Docking Studies",
"url": "https://aperta.ulakbim.gov.tr/record/32521"
}
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