1 Ocak 2018 Dergi makalesi Açık Erişim

Gorgulu, G.; Cicek, M. B.; Dede, B.

Citation Style Language JSON

{
  "DOI": "10.12693/APhysPolA.133.250", 
  "abstract": "A novel ligand, N, N ''-(4-methyl-1,2-phenylene)bis(2-(biphenyl-4-yl)-N'-hydroxy-2-oxoacetimidamide) (H2L) with its Cu(II) and Mn(II) complexes were synthesized in this study. All compounds synthesized were also characterized by H-1- and C-13-NMR, the Fourier transform infrared, elemental analysis, inductively coupled plasma optical emission spectrometry, molar conductivity, magnetic susceptibility measurements and thermogravimetric analysis. Vascular endothelial growth factor-2 (VEGFR-2) and cyclooxygenase-2 (COX-2) inhibition is often used as a parameter for being a potent anticancer agent in docking studies. For this purpose, synthesized and characterized ligand was investigated by molecular docking study to test its inhibitory effect against angiogenic factors VEGFR-2 and COX-2.", 
  "author": [
    {
      "family": "Gorgulu", 
      "given": " G."
    }, 
    {
      "family": "Cicek", 
      "given": " M. B."
    }, 
    {
      "family": "Dede", 
      "given": " B."
    }
  ], 
  "container_title": "ACTA PHYSICA POLONICA A", 
  "id": "32521", 
  "issue": "2", 
  "issued": {
    "date-parts": [
      [
        2018, 
        1, 
        1
      ]
    ]
  }, 
  "page": "250-255", 
  "title": "Novel Aminoketooxime Ligand and Its Cu(II) and Mn(II) Complexes: Synthesis, Characterization and Molecular Docking Studies", 
  "type": "article-journal", 
  "volume": "133"
}